Manifestaciones gastrointestinales y hepáticas de COVID-19 en niños

Villanueva, Mónica; H., Rossana Faundez; Godoy, Marcela

doi:10.32641/rchped.v91i4.2484

Cited by 4 publications

(4 citation statements)

References 27 publications

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“…Os achados dos estudos selecionados apontaram para três premissas acerca das relações entre COVID-19 e sintomas gastrointestinais na população pediátrica. O primeiro pressuposto a ser abordado é de que há um comprometimento intestinal causado pelo vírus da COVID-19, pois o receptor da ECA2 é a ligação celular para o SARS-CoV-2 (51) . Um exemplo disso é que a glicoproteína spike pertencente ao SARS-CoV-2 liga-se na parte extracelular da ECA2 em células hospedeiras, proporcionando altos níveis de expressão do receptor ECA2 (40,52) .…”

Section: Discussionunclassified

Relação entre sintomas gastrointestinais e infecção por COVID-19 na população pediátrica: revisão de escopo

Desconsi,

Araujo,

Furtado

et al. 2024

Rev. esc. enferm. USP

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RESUMO Objetivo: Mapear as evidências na literatura acerca da relação entre sintomas gastrointestinais e a COVID-19 na população pediátrica. Método: Trata-se de scoping review seguindo as recomendações do Instituto Joanna Briggs e PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. A busca foi realizada nas bases: Embase, Google Acadêmico, PubMed, Scopus, LILACS, CINAHL, Scielo, Web of Science e Portal da Biblioteca Virtual em Saúde, entre julho e agosto de 2023. Foram incluídos estudos originais disponíveis na íntegra, em qualquer idioma. Resultados: Foram eleitos 10 estudos que apontaram para três premissas: (1) o receptor ECA 2 é encontrado nas células epiteliais do trato gastrointestinal; (2) os sintomas gastrointestinais são mediados pelo estresse e a infecção é justificada pelo eixo cérebro-intestino; (3) desenvolve o processo de Síndrome Inflamatória Multissistêmica em crianças, afetando o trato gastrointestinal. Conclusão: A síntese de evidências proporcionou três pressupostos os quais orientam a origem dos sintomas gastrointestinais. A identificação dos sintomas gastrointestinais em crianças acometidas por COVID-19 pode auxiliar na abordagem clínica e manejo de cuidados e tratamentos.

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Section: Discussionunclassified

Relação entre sintomas gastrointestinais e infecção por COVID-19 na população pediátrica: revisão de escopo

Desconsi,

Araujo,

Furtado

et al. 2024

Rev. esc. enferm. USP

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“…The findings of the selected studies pointed to three premises about the relationships between COVID-19 and gastrointestinal symptoms in the pediatric population. The first assumption to be addressed is that there is intestinal impairment caused by the COVID-19 virus, as the ACE2 receptor is the cellular link for SARS-CoV-2 (51) . An example of this is that the glycoprotein spike belonging to SARS-CoV-2 binds to the extracellular part of ACE2 in host cells, providing high levels of expression of the ACE2 receptor (40,52) .…”

Section: Retrospective Observational Descriptive and Analyticalmentioning

confidence: 99%

Relationship between gastrointestinal symptoms and COVID-19 infection in the pediatric population: a scoping review

Desconsi,

Araujo,

Furtado

et al. 2024

Rev. esc. enferm. USP

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Objective: To map the evidence in the literature about the relationship between gastrointestinal symptoms and COVID-19 in the pediatric population. Method: This is a scoping review following the recommendations of the Joanna Briggs Institute and PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. The search was carried out on the following bases: Embase, Google Scholar, PubMed, Scopus, LILACS, CINAHL, Scielo, Web of Science and Virtual Health Library Portal, between July and August 2023. Original studies available in full, in any language, were included. Results: Ten studies were chosen that pointed to three premises: (1) the ACE2 receptor is found in the epithelial cells of the gastrointestinal tract; (2) gastrointestinal symptoms are mediated by stress and infection is justified by the gut-brain axis; (3) it develops the process of Multisystem Inflammatory Syndrome in children, affecting the gastrointestinal tract. Conclusion: The synthesis of evidence provided three assumptions which guide the origin of gastrointestinal symptoms. The identification of gastrointestinal symptoms in children affected by COVID-19 can assist in the clinical approach and management of care and treatments.

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“…In children, diarrhoea constitutes the most frequently occurring symptom, often described as mild and self-limiting. In the liver, hypertransaminasaemia usually occurs in patients with a severe progression of the disease, with the incidence ranging from 40% -60% [78]. As opposed to the respiratory secretions, SARS-CoV-2 remains longer in stools, which significantly impacts the spread of disease [79].…”

Section: Multisystem Inflammatory Syndrome In Children (Mismentioning

confidence: 99%

The course of COVID-19 in pediatric patients – specific and non-specific clinical manifestations

Januszewski,

Tobiasz,

Tyczyńska

et al. 2023

J Pre Clin Clin Res.

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Introduction and Objective. COVID-19 caused by SARS-CoV 2 is a still serious danger. The disease which triggered off the COVID-19 pandemic and one of the biggest health crises in many years, began in the city of Wuhan, China, in 2019. The aim of this review is to distinguish most of the specific and non-specific manifestations of the disease among children. Review Methods. The literature review was based on different types of articles including reviews, meta-analyses, systemic reviews, and randomized controlled trials on PubMed, Web of Science, and Scopus databases. Key words featured COVID-19, MIS-C, SARS-CoV-2 manifestations, and specific, and non-specific manifestations of COVID-19. The literature search was performed until September 2023, and concerned only paediatric patients. Brief description of the state of knowledge. Research based on already published studies prevents the forming of firm conclusions. There are different symptoms of COVID-19 infection, some of them are typical, mild, and do not concern medical care units. There are also some non-specific manifestations, often related to multisystem inflammatory syndrome in children (MIS-C), which are more severe and sometimes demand involving intensive care units. Conclusions. A large group of infected children with asymptomatic or present mild symptoms of COVID-19. Nonspecific manifestations, such as cardiovascular, gastrointestinal, psychiatric, neurological, ophthalmic, dermatological, or rheumatological symptoms, can potentially be misleading and require more attention.

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Manifestaciones gastrointestinales y hepáticas de COVID-19 en niños

Cited by 4 publications

References 27 publications

Relação entre sintomas gastrointestinais e infecção por COVID-19 na população pediátrica: revisão de escopo

Relação entre sintomas gastrointestinais e infecção por COVID-19 na população pediátrica: revisão de escopo

Relationship between gastrointestinal symptoms and COVID-19 infection in the pediatric population: a scoping review

The course of COVID-19 in pediatric patients – specific and non-specific clinical manifestations

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