“…Methylphenidate, which blocks dopamine reuptake, was shown to induce hyperlocomotion, which was prevented by lithium, valproate carbamazepine, and antipsychotic drug administration (Nogoceke et al, 2016;Souza et al, 2016;Tonelli et al, 2013;Barbosa et al, 2011;. Moreover, methylphenidate can induce manic-like symptoms in humans (Ekinci et al, 2016;Chakraborty and Grover, 2011;Huey et al, 1981;Smith and Davis, 1977).…”