Mangosteen (Garcinia mangostana): Extraction, purification, bioactivities and toxicities

Abstract

Mangosteen (Garcinia mangostana) is a popular tropical fruit known as ‘the queen of fruits’ due to its delicious flavour. It comprises phytochemicals, flavonoids, and polyphenols such as xanthones, anthocyanins, and phenolic acids. The G. mangostana pericarp, seed, and flesh bioactive compounds have been shown to have anticancer, antitumor, wound healing, anti-inflammatory, antigenotoxic, antioxidative, antimicrobial, and antiviral properties. This review focuses on the bioactivity of G. mangostana, with the most common bioactive compound discovered being xanthone, which is frequently used in cosmetics, antimicrobials, antioxidants, and pharmaceutical research. Various extraction methods, both conventional and non-conventional, have been used in studies, depending on the goal of the research. This review concludes by using a computerised database search technique to discuss the extraction methods available and the properties of the bioactive compounds found in various parts of G. mangostana, including the pericarp, seed, and flesh.

Anthocyanin physiology and biochemistry in fleshy fruit species: Mangosteen as a model

“…The medicinal properties of the pericarp of mangosteen fruit appear to be due to the high concentrations of bioactive compounds, such as tannins, flavonoids, xanthones, and other bioactive substances (Du & Francis, 1977;Pothitirat et al, 2009) and to a rich supply of vitamins, nutrients, and fibers, while being low in calories. The mangosteen pericarp has been shown to contain compounds that can suppress infections (Mattioli et al, 2020;Zamarudin et al, 2023). Perhaps one of mangosteen's most significant attributes is its unique antioxidant profile.…”