Mangiferin attenuates lipopolysaccharide-induced neuronal injuries in primary cultured hippocampal neurons
Hongling Tan,
Dan Liang,
Na Lu
et al.
Abstract:Mangiferin, a naturally occurring potent glucosylxanthone, is mainly isolated from the
Mangifera indica
plant and shows potential pharmacological properties, including anti-bacterial, anti-inflammation, and antioxidant in sepsis-induced lung and kidney injury. However, there was a puzzle as to whether mangiferin had a protective effect on sepsis-associated encephalopathy. To answer this question, we established an
in vitro
cell model of sepsis-associated encephalop… Show more
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