Manganese–methionine chelate improves antioxidant activity, immune system and egg manganese enrichment in the aged laying hens

Abstract

Background It has been reported that supplementation of manganese (Mn) could alleviate the negative effects of age on egg quality in laying hens. However, limited information is available on compensatory ways in order to reduce the adverse effects of hen age on health and Mn deposition in the body. Objectives The objectives were to investigate the effect of organic and inorganic sources of Mn on antioxidant activity, immune system, liver enzymes, shell quality and Mn deposition in the tissues of older laying hens. Methods A total of 250, 80‐week‐old Leghorn laying hens (w36) were allocated into five treatment groups with five replications in a completely randomised design. Treatments were control (without Mn supplementation), 100% Mn sulphate, 75% Mn sulphate + 25% organic Mn chelate, 50% Mn sulphate + 50% organic Mn chelate and 25% Mn sulphate + 75% organic Mn chelate. Results The groups fed 50 and 75% organic Mn chelate exhibited the lowest feed conversion ratio, as well as the maximum laying percentage, and egg weight and mass. Except to those fed 75% Mn sulphate, the hens received Mn supplements either as organic or inorganic, had higher immunoglobulin G and M compared with the control ( p < 0.05). A significant elevation in the values of superoxide dismutase was observed in the hens receiving 50 and 75% organic Mn chelate when compared with the other treatments. The ALP activity decreased with increasing organic Mn chelate. Mn supplementation, either as organic or inorganic, increased Mn deposition in bone, egg yolk and shell, serum and liver. Conclusion Dietary supplementation with 50–75% Mn–methionine has the potential to replace Mn‐sulphate in laying hens’ diet for improving eggshell quality, Mn deposition in the eggshell, antioxidant capacity and immune response, as well as improving laying performance, egg weight and feed conversion ratio.

Evaluation of Egg Quality and Performance in Late-Lay Hens Fed Different Combinations of Copper, Manganese, and Zinc Complexed with Sulfate or Amino Acid Ion

“…It is unclear why the treatment diets produced significant effects on egg weight only during week 10 of the experiment, although this may be attributed to the age of the hens used and corresponding changes in mineral absorption [12]. Khoshbin, Vakili, and Tahmasbi [14] found that feeding late-lay hens a 50/50 or 25/75 ratio of MnSO 4 and AAC Mn increased hen day egg production and egg mass compared to feeding 100% inorganic Mn. Overall, the results of this experiment agree with several previous studies in late-phase laying hens in which feeding AAC or sulfated minerals did not affect egg production [15][16][17][18][19].…”

“…The increased bioavailability of AAC Mn may be enough to counter any impairments in intestinal absorption. Feeding AAC minerals to late-lay hens may even improve intestinal function, including absorption and utilization of said minerals [15], and antioxidative capabilities [14]. Although these parameters were not included in the design of this experiment, they may account for differences in mineral retention.…”

Influence of Dietary Addition of Mineral Shungite and Fucus vesiculosus on Production Performance, Egg Quality, Nutrients Digestibility, and Immunity Status of Laying Hens

“…The quality of eggs of laying hens is an important indicator of poultry production due to the fact that they are considered as a good and economically justified source of high-grade protein in the diet of the human population, especially with limited financial resources [36,37].…”

Worldwide Research Trends for Chelates in Animal Science: A Bibliometric Analysis

“…The shift in research topics from growth and performance in the 1990s to meat quality and antioxidant status in 2010s suggests that increasing numbers of researchers were gradually becoming involved in studies addressing the quality of meat and antioxidant status in farm animals. Several studies have been performed demonstrating the protective and beneficial effects of CTM on animal production, health and, eggshell quality [95], enriched egg content [96] and other metabolic variables in animal nutrition, such as acid-base [30] and antioxidant status [30,96,97]. Therefore, this intellectual structure and network analysis provides insight into the evolution and emerging trends in chelate research and allows researchers to identify key research areas and potential gaps in current research.…”