1998
DOI: 10.1023/a:1008286117771
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Mandibular pain as the leading clinical symptom for metastatic disease: Nine cases and review of the literature

Abstract: Pain of uncertain origin in the jaws should alert clinicians to the potential of metastatic disease in patients with a history of cancer and a bone scintigraphy should be done to rule out metastatic involvement. Although metastatic lesions in this area usually herald generalized neoplastic spread according to our experience, prompt diagnosis nevertheless can lead to useful palliation and an enhanced quality of life.

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Cited by 46 publications
(45 citation statements)
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“…Metastases of rectal adenocarcinoma to the oral cavity are rarely reported. Usually, pain is one of the main symptom of oral metastases [4] , in addition, swelling, bleeding, and paresthesia may be present.…”
Section: Discussionmentioning
confidence: 99%
“…Metastases of rectal adenocarcinoma to the oral cavity are rarely reported. Usually, pain is one of the main symptom of oral metastases [4] , in addition, swelling, bleeding, and paresthesia may be present.…”
Section: Discussionmentioning
confidence: 99%
“…There is evidence of edema, pain, high vascularization of the bone lesion, dental losses, lip and chin paresthesia, symptom that means bone tumor invasion and the commitment of the inferior dental nerve and mental nerve [6].…”
Section: Open Access Http://scidocorg/ijdosphpmentioning
confidence: 99%
“…While a numb chin is a well documented sign of metastatic lesion, other signs and symptoms suggestive of this condition include swelling, severe unremitting pain resembling toothache, facial pain, pathological fracture, limitation of mouth opening, facial and other cranial nerve palsies (17,19,20). The mandible is by far more common than the maxilla as a site for distant spread.…”
Section: Malignancymentioning
confidence: 99%