Managing people with diabetes during the cancer palliation in the era of simultaneous care

Ferrari, P; Giardini, Anna; Negri, Enrica Maria; Villani, G.; Preti, Pietro; Diabetes, Amd

doi:10.1016/j.diabres.2017.12.010

Cited by 4 publications

(1 citation statement)

References 78 publications

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“…Furthermore, DM is, by itself, an increased cause of palliative enrolment in some countries with advanced health system integration as it can be considered as a life-threatening illness 5–7. Evidence-based practice guidelines for the management of DM have been developed by several scientific associations,8–12 which highlight that nutrition, pharmacological therapy, self-monitoring blood glucose and glycated haemoglobin (HbA1c) targets should be individualised for each patient. Additionally, goals should be individualised based on the duration of DM, age or life expectancy, comorbid conditions, known cardiovascular disease or advanced microvascular complications, hypoglycaemia unawareness and individual patient considerations 13.…”

Section: Introductionmentioning

confidence: 99%

Diabetes-related symptoms, acute complications and management of diabetes mellitus of patients who are receiving palliative care: a protocol for a systematic review

et al. 2019

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IntroductionWorldwide, an estimated 40 million people are in need of palliative care each year, but only 14% receive it. The incidence of diabetes mellitus (DM) in patients receiving palliative care is higher than in the general population. This association is intended to grow as a result of the rising burden of DM worldwide, ageing populations and the improved overall survival time of several diseases over the last few decades. Recommendations for DM management in the context of palliative care are mainly based on expert opinion as there is a lack of suitable evidence base and randomised clinical trials in palliative care are scarce. The aim of our systematic review is to identify the best DM management practices in order to reduce important DM-related symptoms and acute complications in patients receiving palliative care.Methods and analysisThe authors will study the DM treatment and management literature, surveying the different approaches employed to treat adult palliative patients. Core health bibliographic databases will be searched from January 1990 to May 2019. Data sources will include Ovid MEDLINE, Embase, PubMed, Web of Sciences, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, Cumulative Index to Nursing and Allied Health Literature and grey literature. Details regarding diet, oral and injectable glucose-lowering medicines, insulin regimens and blood glucose monitoring strategies will be evaluated. We defined the primary outcomes to compare between DM management approaches as the presence of symptoms (polyuria, polydipsia and polyphagia) and acute complications of DM (hypoglycaemia, hyperglycaemic hyperosmolar state and diabetic ketoacidosis), and secondary outcomes as hospital admissions and deaths due to DM-related complications, health-related quality of life and glycaemic control.Ethics and disseminationThe systematic review methodology does not require ethics approval due to the nature of the study design. The results of the systematic review will be published in a peer-reviewed journal and will be publicly available.PROSPERO registration numberCRD42018115772.

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Section: Introductionmentioning

confidence: 99%

Diabetes-related symptoms, acute complications and management of diabetes mellitus of patients who are receiving palliative care: a protocol for a systematic review

et al. 2019

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Hospitalization as an Opportunity to Optimize Glycemic Control in Oncology Patients

2019

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Glycemic control and cancer outcomes in oncologic patients with diabetes: an Italian Association of Medical Oncology (AIOM), Italian Association of Medical Diabetologists (AMD), Italian Society of Diabetology (SID), Italian Society of Endocrinology (SIE), Italian Society of Pharmacology (SIF) multidisciplinary critical view

Natalicchio,

Marrano,

Montagnani

et al. 2024

J Endocrinol Invest

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Background: Increasing evidence suggests that diabetes increases the risk of developing different types of cancer. Hyperinsulinemia, hyperglycemia and chronic inflammation, characteristic of diabetes, could represent possible mechanisms involved in cancer development in diabetic patients. At the same time, cancer increases the risk of developing new-onset diabetes, mainly caused by the use of specific anticancer therapies. Of note, diabetes has been associated with a ∼10% increase in mortality for all cancers in comparison with subjects who did not have diabetes. Diabetes is associated with a worse prognosis in patients with cancer, and more recent findings suggest a key role for poor glycemic control in this regard. Nevertheless, the association between glycemic control and cancer outcomes in oncologic patients with diabetes remains unsettled and poorly debated. Purpose: The current review seeks to summarize the available evidence on the effect of glycemic control on cancer outcomes, as well as on the possibility that timely treatment of hyperglycemia and improved glycemic control in patients with cancer and diabetes may favorably affect cancer outcomes.

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Managing people with diabetes during the cancer palliation in the era of simultaneous care

Cited by 4 publications

References 78 publications

Diabetes-related symptoms, acute complications and management of diabetes mellitus of patients who are receiving palliative care: a protocol for a systematic review

Diabetes-related symptoms, acute complications and management of diabetes mellitus of patients who are receiving palliative care: a protocol for a systematic review

Hospitalization as an Opportunity to Optimize Glycemic Control in Oncology Patients

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