Management strategies for patients with nipple discharge

Göksel, Hüsnü A.; Yağmurdur, Mahmut Can; Demirhan, Beyhan; Işıklar, I.; Karakayalı, H.; Bi̇lgi̇n, N; Haberal, Mehmet

doi:10.1007/s00423-004-0515-6

Cited by 16 publications

(22 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nipple discharge is the third most common reason for presentation to a breast clinic (3) . Conservative management of patients with ductectasia of the breast with antibiotics does not cure the condition, and the patients were still complaining of nipple discharge and noncyclic mastalgia.…”

Section: Discussionmentioning

confidence: 99%

“…Ductal imaging by ductography is helpful in detecting ductal carcinoma of the breast but it is non-specific (8) . Ductography has a highpositive predictive value in the diagnosis of intra ductal lesions, papilloma and carcinoma; however, it has a low sensitivity and is painful (3) .…”

Section: Discussionmentioning

confidence: 99%

“…Ductectasia affects primarily middle-aged to elderly women but can occasionally occur in children (2) . Nipple discharge is the third most common reason for presentation to a breast clinic (3) . In cases of ductectasia, the dilated lactiferous ducts are filled with a stagnant brown or green secretion which may discharge.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

2017

IJMS

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

2017

IJMS

View full text Add to dashboard Cite

show abstract

“…[8] However, malignancies of various grades are detected in 4% to 28% of patients with PND. [5,6] Therefore, exclusion of malignancy is essential in these patients.…”

Section: Discussionmentioning

confidence: 99%

“…[3,4] Pre-malignant or malignant lesions constitute the source of the discharge in 5% to 28% of PND cases. [5,6] As such, the etiology of PND must be researched very carefully.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of minimally invasive Microductectomy versus Major Duct Excision in the diagnosis and treatment of patients with pathologic nipple discharge

Çetin¹

2017

South Clin Ist Euras

View full text Add to dashboard Cite

Objective: The present study is a comparison of results in patients with pathological nipple discharge (PND) who underwent microductectomy and those who underwent major duct excision (MDE). Methods:This study included patients who underwent surgery in the clinic due to PND between October 2015 and October 2011. Data were collected via retrospective chart review. The patients were divided into 2 groups according to the type of surgery (Group Micro and Group Major). The demographic characteristics of the patients, the character of the discharge, preoperative imaging findings, preoperative cytological findings, postoperative pathological findings, and follow-up results were analyzed. Results:The records of a total of 78 patients were examined. Group Micro comprised 57 patients, and 21 were included in Group Major. The most frequently observed lesion in both groups was papillomatous lesion without atypia (Group Major: n=8, 38.1% and Group Micro: n=26, 45.6%). Premalignant lesion was detected in 17 patients (atypical ductal hyperplasia, papillomatous lesion with atypia, ductal carcinoma in situ, intraductal papillary carcinoma). Although the number of patients with a premalignant lesion in Group Major was greater than that seen in Group Minor, the difference was not significant (n=11, 19.3% and n=6, 28.6%, respectively; p=0.3). Conclusion:Conventional imaging and cytology techniques are usually insufficient in the diagnosis of PND. Therefore, surgery is frequently required in these patients. Microductectomy or MDE may be selected as the preferred surgical procedure. In this study, the results of the 2 procedures were found to be similar.

show abstract

Bloody nipple discharge is a predictor of breast cancer risk: a meta-analysis

Chen

Zhou

Zhao

et al. 2011

Breast Cancer Res Treat

View full text Add to dashboard Cite

Nipple discharge is a common complaint of patients with breast disease. The color of nipple discharge is always the first alarming symptom for patients. It is controversial whether the discharge color is an indicator of an underlying malignancy. The electronic database PubMed was searched for relevant articles. A meta-analysis about the association between the color of nipple discharge and breast cancer risk was conducted. Eight studies, including 3,110 patients, were eligible for this meta-analysis. Compared with patients in non-bloody nipple discharge group (179/1,478), patients in bloody nipple discharge group (404/1,632) had a markedly higher breast cancer risk (OR: 2.27, 95% CI: 1.32-3.89, P < 0.001 for heterogeneity). Compared with patients in clear/serous group (71/575), patients in bloody nipple discharge group (326/1,271) also had a higher risk (OR: 2.49, 95% CI: 1.25-4.93, P = 0.011 for heterogeneity). Furthermore, compared with patients in the colored group (55/448), patients in bloody nipple discharge group (296/1,124) (OR: 2.00, 95% CI: 0.74-5.45, P = 0.009 for heterogeneity) had no significant difference. Besides, there was no significant difference between patients in colored group (55/448) and clear/serous group (61/470) (OR: 1.35, 95% CI: 0.83-2.18, P = 0.707 for heterogeneity). Therefore, bloody nipple discharge could be a predictor of breast cancer risk among different colors of discharges. The symptom of bloody nipple discharge is helpful to the stratification of preoperative patients.

show abstract

Management strategies for patients with nipple discharge

Cited by 16 publications

References 22 publications

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

Comparative analysis of minimally invasive Microductectomy versus Major Duct Excision in the diagnosis and treatment of patients with pathologic nipple discharge

Bloody nipple discharge is a predictor of breast cancer risk: a meta-analysis

Contact Info

Product

Resources

About