Atmospheric particle matters which have many negative effects to the environment and human health have raised the public awareness in last years. Urban centers, through their specific activities, generate a new and complex form of pollution that affects all the quality factors, including those of the environment, the population being the main victim. This paper presents the status of PM2.5 in the air of T�rgu-Jiu city for for 2015-2017, and assessment of the effect of meteorological factors to the values of PM2.5 content. The results indicate that from the three years under study, the annual PM2.5 concentration values exceeded the admissible limit value only for 2015. The highest pollution levels occurred during the months of February, March, October and November of the three analyzed years due to a higher fuel consumption for heating. Regarding the effect of meteorological factors such as: rainfall and temperature to the PM2.5 level, it was observed a decrease of the concentration of PM2.5 as air humidity increases and an increase of PM2.5 concentration as air temperature decreases.