Management of Vertebral Metastasis in Patients With Uterine Cervical Cancer

Abstract

We found that patients with lymphovascular space invasion were at high risk of isolated VM and that the survival times after CT and CRT were similar. Because most VMs are seen in the vertebral space within the borders of radiation therapy, borders of external beam radiotherapy should be carefully determined for each patient.

<p>Clinical Characteristics and Prognostic Analysis of Gynecologic Cancer with Spinal Metastases: A Single-Center Retrospective Study</p>

“… 1 – 3 However, some patients still relapse or develop metastases within 2‒3 years after treatment. 4 , 5 Many patients develop pelvic or distant metastases during or after treatment, which can be metastatic to bones, liver, brain, lungs or kidneys. In China, GC accounts for about 12% of all cancer types in women.…”

Clinical Characteristics, Treatment Modalities, and Potential Contributing and Prognostic Factors in Patients with Bone Metastases from Gynecological Cancers: A Systematic Review

“…However, in most patients, the bone metastases diagnosis was made at time of the primary tumor diagnosis [ 39 , 40 , 46 ]. The main reported bone metastases sites were the spine and pelvis, with bone metastases present in single and multiple sites and with pain as the principal reported symptom [ 36 , 37 , 39 , 40 , 41 , 42 , 45 ]. Extraosseous metastases were described by almost all studies, but none of them specified the anatomical sites.…”

“…Ovarian cancer Deng et al 2018 [18] NA NA NA Sehouli et al 2013 [19] NA NA NA Zhang et al 2013 [20] CD NA NA NA Zhang et al 2019 [21] NA NA NA Endometrial cancer Guo et al 2020 [22] NA NA NA Hong et al 2021 [23] NA NA NA Kimyon et al 2016 [24] NA NA NA Li et al 2020 [25] NA NA NA Liu et al 2020 [26] NA NA NA Mao et al 2020 [27] NA NA NA McEachron et al 2020 [28] NA NA NA Ouldamer et al 2019 [29] NA NA NA Takeshita et al 2016 [30] NA NA NA Uccella et al 2013 [31] NA NA NA Yoon et al 2014 [32] NA NA NA Uterine sarcoma Bartosh et al 2017 [33] NA NA NA Tirumani et al 2014 [34] NA NA NA Vulvar cancer Prieske et al 2016 [35] NA NA NA Cervical cancer Kanayama et al 2015 [36] NA NA NA Kocaer et al 2018 [37] NA NA NA Lin et al 2018 [38] NA NA NA Makino et al 2016 [39] NA NA NA Manders et al 2018 [40] NA NA NA Matsumiya et al 2016 [41] NA NA NA Nartthanarung et al 2014 [42] NA NA NA Sethi et al 2019 [43] NA NA NA Yin et al 2019 [44] NA NA NA Yoon et al 2013 [45] NA NA NA Zhang et al 2018 [46] NA NA NA Zhang et al 2020 [47] NA NA NA Zhou et al 2020 [48] NA NA NA Acknowledgments: This work was supported by IRCCS Istituto Ortopedico Rizzoli (Ricerca Corrente).…”

Outcomes of Surgical Decompression for Spinal Metastases From Gynecological Cancers: A Retrospective Cohort Study

“…When the tumor infiltrates the spine which made up 52.8% of all bone metastases pain, pathological fractures, and disability are among the most common signs and symptoms. Hence, a decrease in survival rate is observed due to a high systemic tumor burden yielding a reduction of Quality of Life (QoL) caused by disability, severe mechanical pain, and neurological deficits [6,8].…”