Management of Venous Thromboembolism: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians

Snow, Vincenza; Qaseem, Amir; Barry, Patricia P.; Hornbake, E. Rodney; Rodnick, Jonathan E; Tobolic, Timothy; Ireland, Belinda; Segal, Jodi B; Bass, Eric B.; Weiss, Kevin B.; Green, Lee A.; Owens, Douglas K; Aronson, Mark D.; Casey, Donald E.; Cross, J. Thomas; Dolan, Nancy C.; Fitterman, Nick; Shekelle, Paul G; Sherif, Katherine; Wall, Erika; Peterson, Kevin; Gill, James M.; Marshall, Robert C.; Schellhase, Kenneth G.; Strode, Steven W.; Elward, Kurt; Mold, James W.; Temte, Jonathan L.; Chen, Frederick M.; Koinis, Thomas F.; Powers, Donya A.; Kochendorfer, Karl M.; Oppelt, Peter; Young, Herbert F.; Schoof, Bellinda

doi:10.1370/afm.668

Cited by 77 publications

(69 citation statements)

References 80 publications

(100 reference statements)

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“…1,2 Heparin anticoagulation is the standard of care for DVT treatment and is proven to significantly reduce the risk of PE, as well as recurrent DVT. 3,4 A recent report suggests that rapid anticoagulation with low-molecular-weight heparin (LMWH) may decrease the incidence of post-thrombotic syndrome, but the mechanisms are not clear, and patient heterogeneity in outcomes exists. 5 The mechanical and inflammatory insult caused by an acute DVT is now fairly well characterized in animal models.…”

mentioning

confidence: 99%

Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin

Moaveni

Lynch

Luke

et al. 2008

Journal of Vascular Surgery

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How the vein wall endothelium responds after deep vein thrombosis (DVT) has not been well documented owing to limited human specimens. This report shows that low-molecular-weight heparin accelerates or protects the endothelium and preserves medial smooth muscle cell integrity after DVT, but that this effect is limited to a relatively early time period. Although most DVT prophylaxis is pharmacologic (a heparin agent), use of nonpharmacologic measures is also common. The use of heparin prophylaxis, compared with after DVT treatment, and the acceleration of post-DVT re-endothelialization require clinical correlation.

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mentioning

confidence: 99%

Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin

Moaveni

Lynch

Luke

et al. 2008

Journal of Vascular Surgery

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“…Thus, only recommendations for reporting standards can be made [43, [67][68][69]. The American College of Physicians and the American Academy of Family Physicians recently concluded that there was insufficient evidence to make any recommendations with respect to the use of caval filters [70].…”

Section: Evidence For Optional Filters?mentioning

confidence: 99%

Optional inferior vena caval filters: where are we now?

2008

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With the advent of newer optional/retrievable inferior vena caval filters, there has been a rise in the number of filters inserted globally. This review article examines the currently available approved optional filter models, outlines the clinical indications for filter insertion and examines the expanding indications. Additionally, the available evidence behind the use of optional filters is reviewed, the issue of anticoagulation is discussed and possible future filter developments are considered.

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“…Both medications reduce the risk of DVT and subsequently PE, but patients given LMWH have significantly fewer bleeding episodes than those treated with UFH. [32][33][34] How the drug is absorbed may impact its efficacy. Absorption of UFH from subcutaneous tissues is variable due to its large molecular size and interaction with plasma proteins and macrophages.…”

Section: Thrombus Formation and The Obese Patientmentioning

confidence: 99%

DVT Prevention for the Obese Patient: Evidence-Based Nursing Interventions

Maiocco

2008

Bariatric Nursing and Surgical Patient Care

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Obesity is a risk factor for deep vein thrombosis (DVT), and as obesity increases, DVT rates will also elevate. The purpose of this article is to assist nurses in correctly selecting evidence-based interventions found effective in preventing DVT formation. To promote full understanding of this disease process, pathophysiologic changes associated with obesity will be linked with current research-based therapies of anticoagulation, compression therapy, and mobilization. A call for future research is proffered in multiple areas, to include assessment, determination of interventional effectiveness, and establishment of outcome measurements for both surgical and medical obese populations.

show abstract

Management of Venous Thromboembolism: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians

Cited by 77 publications

References 80 publications

Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin

Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin

Optional inferior vena caval filters: where are we now?

DVT Prevention for the Obese Patient: Evidence-Based Nursing Interventions

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