Management of Trastuzumab Deruxtecan-related nausea and vomiting in real-world practice
Giulia Notini,
Matteo Maria Naldini,
Lorenzo Sica
et al.
Abstract:BackgroundNausea and vomiting are common side effects of Trastuzumab Deruxtecan (T-DXd), but guidelines for optimal management were not initially available. This retrospective single-center study aimed at evaluating the efficacy of two antiemetic regimens in patients receiving T-DXd.MethodsData from metastatic breast cancer patients receiving T-DXd were collected. Two groups were defined: patients treated with 5-HT3 receptor antagonists (RA) ± dexamethasone (5-HT3-group) and patients treated with a fixed oral … Show more
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