2004
DOI: 10.1007/s00259-004-1680-0
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Management of thyroid nodules: a clinicopathological, evidence-based approach

Abstract: Management of thyroid nodules is one of the most controversial issues in thyroidology. Different approaches derive from geographical variation in presentation, inadequate or incomplete clinical diagnosis, lack of prospective controlled studies and, frequently, the different cultural backgrounds of physicians. This review aims to offer a practical approach to the management of nodular thyroid disorders, considering the way in which the pathophysiology of the disease provides clues to the correct clinical diagno… Show more

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Cited by 52 publications
(21 citation statements)
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“…Thyroid nodules do not reflect a single disease but are the clinical manifestation of a wide spectrum of different thyroid diseases (7). In a normal gland or a diffuse goiter, thyroid nodules may be solitary or multiple (8).…”
Section: Evaluation Of Thyroid Nodulesmentioning
confidence: 99%
“…Thyroid nodules do not reflect a single disease but are the clinical manifestation of a wide spectrum of different thyroid diseases (7). In a normal gland or a diffuse goiter, thyroid nodules may be solitary or multiple (8).…”
Section: Evaluation Of Thyroid Nodulesmentioning
confidence: 99%
“…If the nodule is hot, observation is sufficient in euthyroid patients. If the nodule is cold, surgery is warranted [8]. Since most nodules are cold on a scan and only a small minority is malignant, this adds to the inefficiency surrounding RAI scanning [9].…”
Section: Discussionmentioning
confidence: 99%
“…Узлы ЩЖ являются не каким то одним заболе ванием, а представляют собой клиническую мани фестацию различной патологии этого органа [7]. Они могут появляться в неизмененной ЩЖ или на фоне диффузного зоба, могут быть одиночными или множественными [8].…”
Section: обследование пациентов с узловым зобомunclassified
“…Хотя широкое применение УЗИ и ограничило использование тиреоидной сцинтиграфии, но эта методика полезна для подтверждения функциональ ной природы узла ЩЖ при низких или неопределя емых значениях ТТГ в сыворотке крови, так как она зачастую демонстрирует наличие автономно функ ционирующих узлов [7].…”
Section: низкийunclassified