Management of the N0 neck in moderately advanced squamous carcinoma of the larynx

Abstract

This study confirmed the adequacy of SND as a satisfactory staging and therapeutic procedure, and suggests its use in the treatment of limited node-positive (N+) neck.

Modified radical neck dissection vs. selective neck dissection: an analysis of lymph node yield and post-surgical outcomes

“…Previous reports of total lymph node yield do exist and have, unsurprisingly, demonstrated significant variance between the MRND and SND. Dias et al [13] found the mean number of nodes dissected per SND, and MRND was 18 (range 12-23 nodes) and 39 (range 32-45 nodes), which was also a trend observed in this study. The importance of lymph node yield has been previously established [18].…”

“…However, given the high levels of variability amongst patient cohorts, primary cancer locations and pre-surgery staging, such a trial would be difficult to Dias et al [13] 2009 Larynx Patel et al [14] 2008 Oropharynx, hypopharynx, oral cavity and larynx N1-N3 complete. Future research is likely to move on to less invasive techniques that do not compromise efficacy, such as the super selective and robot-assisted neck dissections [21,15,2].…”

“…A total of 181 distinct articles were retrieved. Of these, seven were direct comparisons of MRND vs. SND (or MRND/RND vs. SND) where SCC was the primary lesion [11][12][13][14][15][16][17] and mortality/ recurrence rates were investigated. Six were retrospective studies and one, Robbins et al [15], was prospective.…”

“…This is because direct comparisons of the MRND and SND are problematic due to high levels of variability amongst patient cohorts and treatment regimens. Current studies that directly compare the MRND and SND have tended to focus on mortality and recurrence rates for a variety of primary SCC locations and pre-operative SCC grades [11][12][13][14][15][16][17], though correlation of this data is not yet available. Furthermore, the current literature is lacking in terms of direct comparisons of the MRND and SND concerning variables such as lymph node yield and postoperative complication rates.…”

Utility of positron‐emission tomography/computed tomography imaging in the management of the neck in recurrent laryngeal cancer

“…Kligerman et al examined 76 patients with clinically T3/T4 N0 SCC of the larynx and found a 30% frequency of occult neck disease 15. This study was later expanded by Dias et al to 327 patients, where the occurrence of occult cervical metastases was 21.4% 16…”