2018
DOI: 10.1093/jscr/rjy142
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Management of T-cell large granular lymphocyte leukemia and concurrent retroperitoneal liposarcoma

Abstract: T-cell large granular leukemia (T-LGL) is a rare lymphoproliferative disorder characterized by the clonal expansion of cytotoxic T lymphocytes. We present a unique case of T-LGL and concurrent retroperitoneal sarcoma occurring in a patient with long-standing rheumatoid arthritis. Pathology revealed a high-grade dedifferentiated liposarcoma. The diagnosis of T-LGL with a synchronous retroperitoneal sarcoma is a case that highlights the surgical management of these two rare conditions.

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“…Of the remaining six studies, one was a retrospective case series (26) and five were case reports (70)(71)(72)(73)(74), both documenting the recurrence and survival outcomes of RPLPS patients receiving R1-margin resection for RPLPS. In total, our systematic review evaluated a total of 552 patients with RPLPS of whom 346 underwent R0-margin resection and 206 underwent R1-margin resection.…”
Section: R1-margin Resectionmentioning
confidence: 99%
“…Of the remaining six studies, one was a retrospective case series (26) and five were case reports (70)(71)(72)(73)(74), both documenting the recurrence and survival outcomes of RPLPS patients receiving R1-margin resection for RPLPS. In total, our systematic review evaluated a total of 552 patients with RPLPS of whom 346 underwent R0-margin resection and 206 underwent R1-margin resection.…”
Section: R1-margin Resectionmentioning
confidence: 99%