Dental implantology has transformed restorative dentistry by providing effective solutions for tooth replacement. However, challenges like peri-implantitis, involving inflammation and bone loss around dental implants, have emerged. This article explores the prosthetic management of peri-implantitis, emphasizing risk analysis and preventive strategies. Peri-implantitis's definition, clinical signs, and causes are outlined, encompassing local and systemic risk factors. Prosthodontists play a key role in removing prosthetic components, enabling thorough treatment. Mechanical and chemical methods for implant surface debridement are highlighted, focusing on infection removal and tissue healing. Preventive measures, such as patient evaluation, hygiene education, and treatment planning, are crucial for pre- and post-implant placement. Structured maintenance schedules, interdisciplinary collaboration, and customized prosthetic designs are pivotal in preventing recurrence. This comprehensive approach ensures implant longevity and elevates implant dentistry standards.