Management of strictures after radiotherapy for esophageal cancer

Ng, Tony W.; Spencer, G M; Sargeant, Ian; Thorpe, Sally; Bown, Stephen G.

doi:10.1016/s0016-5107(96)70196-7

Cited by 28 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This patient had received both EBRT and a brachytherapy boost, supporting the argument that this is a dose-related phenomenon that can be avoided. 104,105 As a consequence of the comparable morbidity there were no differences in in-hospital or 30-day mortality between the treatment arms or groups; 14 patients (44%) had an unexplainable deterioration in their physical condition following treatment to death, with no specific cause found. Some of these patients may well have had concealed haemorrhage or unrecognised aspiration, since these were the most common recognised causes of death and occurred equally between treatment groups.…”

Section: Mortality and Complicationsmentioning

confidence: 88%

“…103 Treatment leads to intractable nausea and vomiting if the fields include the stomach, and fibrous cicatrisation requiring dilatation or salvage intubation occurs in 30-50%, especially with higher doses. 104,105 As a result of this morbidity, 30% of patients starting a course of oesophageal radiotherapy do not complete it. 68 Treatmentrelated mortality is rare, but mortality figures may be distorted as treatment is usually terminated when a patient becomes too ill to continue.…”

Section: Radiotherapymentioning

confidence: 99%

See 1 more Smart Citation

A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer

Shenfine

McNamee²,

Steen³

et al. 2005

Health Technol Assess

View full text Add to dashboard Cite

It was suggested that rigid tubes and 24-mm SEMS should no longer be recommended and bipolar electrocoagulation and ethanol tumour necrosis should not be used for primary palliation. The choice in palliation would between non-stent and 18-mm SEMS treatments, with non-stent therapies being made more available and accessible to reduce delay. A multidisciplinary team approach to palliation is also suggested. A randomised controlled clinical trial of 18-mm SEMS versus non-stent therapies with survival and quality of life end-points would be helpful, as would an audit of palliative patient admissions to determine the reasons and need for inpatient hospital care, with a view to implementing cycle-associated change to reduce inpatient stay. A study of delays in palliative radiotherapy treatment is also suggested, with a view to implementing cycle-associated change to reduce waiting time.

show abstract

Section: Mortality and Complicationsmentioning

confidence: 88%

Section: Radiotherapymentioning

confidence: 99%

A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer

Shenfine

McNamee²,

Steen³

et al. 2005

Health Technol Assess

View full text Add to dashboard Cite

show abstract

“…[56][57][58][59] Radiation-induced strictures have also been reported to have a high rate of dilation-related adverse events, 60 but this risk may be related to the presence of malignancy rather than the effect of radiation. 61 Pain is the most common symptom related to perforation. 25,26,62,63 Fever, crepitus, pleuritic chest pain, leukocytosis, and pleural effusion may also be present.…”

Section: Adverse Events Of Ugi Dilationmentioning

confidence: 99%

Adverse events of upper GI endoscopy

Ben–Menachem¹,

Decker²,

Early³

et al. 2012

Gastrointestinal Endoscopy

303

170

View full text Add to dashboard Cite

“…An upper gastrointestinal series three weeks after dilation did not reveal a fistula, suggesting that dilation was not causative. Previous studies have shown that esophageal dilation can be safely performed after radiotherapy [19,20], without increased risk of perforation [19]. …”

Section: Discussionmentioning

confidence: 99%

Synovial sarcoma leading to a paraesophageal abscess in a child.

et al. 2012

View full text Add to dashboard Cite

SummaryBackground:Synovial sarcoma (SS) is an uncommon malignant neoplasm arising from primitive pluripotential mesenchyme primarily affecting the soft tissues of the extremities. Rarely other locations are involved, including the mediastinum.Case Report:After treatment for mediastinal SS by surgical resection, radiation therapy, and chemotherapy, an 11-year-old boy developed an esophageal stricture and fistula, the latter resulting in a paraesophageal abscess. Management of the esophageal stricture and fistula required a multi-disciplinary approach. We report our experience with the management of this difficult complication, as well as a brief review of the literature on SS.Conclusions:Rare conditions, particularly those with unusual complications, present therapeutic challenges requiring a multi-disciplinary team approach. Reporting experiences with difficult cases can benefit providers faced with similar problems in the future.

show abstract

Management of strictures after radiotherapy for esophageal cancer

Cited by 28 publications

References 14 publications

A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer

A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer

Adverse events of upper GI endoscopy

Synovial sarcoma leading to a paraesophageal abscess in a child.

Contact Info

Product

Resources

About