Management of pulmonary embolism during acrylic vertebroplasty

Tozzi, Piergiorgio; Abdelmoumene, Yasmine; Corno, Antonio F.; Gersbach, P; Hoogewoud, Henri-Marcel; Segesser, Ludwig K. von

doi:10.1016/s0003-4975(02)03962-0

Cited by 172 publications

(103 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Acute cardiovascular consequences of considerable PMMA leaks (2 mL) may not be severe in persons with a healthy cardiopulmonary system. Subsequently adding hydroxyapatite (10%) to PMMA cement did not result in more severe cardiovascular changes [52]. It is also possible that thromboembolism may also aggravate cardiovascular deterioration after PMMA embolism.…”

Section: Intra-cardiac Embolism Leading To Cardiovascular Deteriorationmentioning

confidence: 95%

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Shridhar¹,

Chen²,

Khalil³

et al. 2016

Preprint

View full text Add to dashboard Cite

Percutaneous vertebroplasty procedure is of major importance, given the significant increasing aging population and higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main features of PMMA bone cement on the heart, and the extent of influence of materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case report.

show abstract

Section: Intra-cardiac Embolism Leading To Cardiovascular Deteriorationmentioning

confidence: 95%

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Shridhar¹,

Chen²,

Khalil³

et al. 2016

Preprint

View full text Add to dashboard Cite

show abstract

“…Most cases of pulmonary cement embolism seem to be asymptomatic. However, a growing number of reports list symptoms ranging from chest pain and dyspnea 5,10,11 to acute respiratory distress syndrome 12,13 and even death. 6,7,14 The incidence of pulmonary cement embolism may increase further with the growing number of vertebroplasty interventions.…”

mentioning

confidence: 99%

Cardiovascular Changes after Pulmonary Cement Embolism: An Experimental Study in Sheep

Krebs¹,

Aebli²,

Goss³

et al. 2007

American Journal of Neuroradiology

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE:Most cement leaks during vertebroplasty are asymptomatic, but pulmonary cement embolism has been reported to cause cardiovascular disturbances and even death. Adding hydroxyapatite (HA) to polymethylmethacrylate (PMMA) cement to reduce the quantity of barium may aggravate cardiovascular deterioration in the event of cement embolism by activating coagulation. Thus, we investigated the cardiovascular changes after pulmonary cement embolism of PMMA with and without HA.

show abstract

“…Symptomatic cement embolisms can be recognized by their clinical signs and symptoms such as dyspnea/tachypnea, tachycardia, cyanosis, chest pain, coughing, hemoptysis, dizziness and sweating whereas it is more difficult to recognize asymptomatic cement embolisms [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Late onset of pulmonary cement embolism after a regular vertebroplasy. A clinical documentation

2013

View full text Add to dashboard Cite

AbstractVertebroplasty is a new minimal-invasive procedure for the treatment of painful vertebral fractures. The risk of a pulmonary embolism ranges from 3.5 to 23% for osteoporotic fractures. However, data about the incidence and treatment strategies of pulmonary cement embolisms (PCE) are limited. We report a case of a patient with symptomatic pulmonary cement embolism after the vertebroplasty. The diagnosis was confirmed by means of CT- scan. In cases of asymptomatic patients with peripheral PCE we recommend no treatment besides clinical follow-up. In our case of symptomatic embolisms, we recommend to proceed according to the guidelines regarding the treatment of thrombotic pulmonary embolisms, which includes initial heparinization and a following 6-month coumarin therapy.

show abstract

Management of pulmonary embolism during acrylic vertebroplasty

Cited by 172 publications

References 2 publications

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Cardiovascular Changes after Pulmonary Cement Embolism: An Experimental Study in Sheep

Late onset of pulmonary cement embolism after a regular vertebroplasy. A clinical documentation

Contact Info

Product

Resources

About