Management of Psoriasis in Children: a Narrative Review

Hajheydari, Zohreh; Sarparast, Leila; Shahmohammadi, Soheila

doi:10.5812/jpr.131

Cited by 4 publications

(3 citation statements)

References 44 publications

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“…Kontraindikasi fototerapi UV mencakup riwayat gangguan herediter terkait karsinogenesis yang diinduksi oleh UV. [16][17] Tabel 2. Indikasi dan kontraindikasi fototerapi [16][17] Indikasi Efek samping yang dapat terjadi segera setelah fototerapi meliputi sunburn-like reaction (kulit merah dan nyeri), rasa terbakar ringan atau tersengat, titik-titik gelap pada kulit (umumya pada pasien kulit gelap), gatal, lepuh (jarang), terbakar (jarang).…”

Section: Kontraindikasi Dan Efek Sampingunclassified

“…[16][17] Tabel 2. Indikasi dan kontraindikasi fototerapi [16][17] Indikasi Efek samping yang dapat terjadi segera setelah fototerapi meliputi sunburn-like reaction (kulit merah dan nyeri), rasa terbakar ringan atau tersengat, titik-titik gelap pada kulit (umumya pada pasien kulit gelap), gatal, lepuh (jarang), terbakar (jarang). Sedangkan efek samping jangka panjang yang dapat terjadi yaitu freckles, kulit menua lebih awal (kerutan, kulit tidak kencang, itnik penuaan), dan meningkatnya risiko kanker kulit.…”

Section: Kontraindikasi Dan Efek Sampingunclassified

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Fototerapi dalam Dermatologi

Aryani¹,

Gozali²,

Widyasari³

2020

Dies

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ABSTRAKFototerapi merupakan prosedur terapeutik yang umum digunakan dalam bidang dermatologi. Fototerapimenggunakan cahaya ultraviolet dengan gelombang tertentu, diklasifikasikan dalam 3 kelompok yaitu broadband UVB(BBUVB), narrowband UVB (NBUVB), serta psoralen kombinasi dengan UVA (PUVA). Saat ini NBUVB lebihbanyak digunakan dalam terapi dermatosis tertentu antara lain psoriasis, dermatitis atopik dan vitiligo. Mekanisme kerjafototerapi yaitu menurunkan proliferasi epidermis, menekan sistem imun, mengurangi proses inflamasi, danrepigmentasi. Dosis fototerapi harus disesuaikan dengan berdasar tipe kulit dan minimal eryhtema dose (MED) padaawal terapi. Frekuensi terapi ditentukan berdasar berat-ringan penyakit, dilakukan secara kontinu. Selain manfaatterapeutik, beberapa kontraindikasi dan efek samping yang perlu diperhatikan dalam penggunaan fototerapi ini antaralain interaksi obat, fotoalergik dan risiko keganasan kulit.

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Section: Kontraindikasi Dan Efek Sampingunclassified

Fototerapi dalam Dermatologi

Aryani¹,

Gozali²,

Widyasari³

2020

Dies

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“…This disease affects 4% of all children below 16 years of age with all types of dermatologic disorders [18]. The various forms of psoriasis have been known thus far; plaque psoriasis (characterized by dry scaly patches), pustular psoriasis (contains pus like fluid mainly infiltrated with white blood cells), erythrodermic psoriasis (characterized by exfoliation of fine scaly skin with pain and itching), guttate psoriasis (characterized by drop like dots), inverse psoriasis (affects the flexure surfaces and characterized by smooth inflamed lesions) and scalp and nail psoriasis.…”

Section: Introductionmentioning

confidence: 99%

Association between psoriasis and ocular disorders: A narrative review

Algarni¹,

AlMuqrin²,

Alarwan³

2017

Clin Med Invest

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Psoriasis is a long lasting immunological assisted skin disease along with many extra cutaneous manifestations, with substantial genetic and environmental influences. It affects about 1.5-3% of the world's population, though commonly not life threatening, but then again causes significant morbidity and has no remedy. We conducted a systematic search on the sites like Pub Med, Embase, Scopus, and multiple databases. The literature search included MeSH-terms and text words, in the following combination such as Blepharitis, dry eye, psoriasis, uveitis, immunological assisted skin disease. No restrictions were followed in terms of publication dates. The reference lists of included articles were screened for additional references. Psoriatic ocular findings may include conjunctivitis, dry eye, blepharitis, squamous intraepithelial neoplasm of the conjunctiva, corneal abscess and immune-mediated conditions such as uveitis, all of which may lead to articular changes. Its pathogenesis is very complicated and involves many molecules like T cells, APCs, keratinocytes, Langerhans cell, macrophages, NK cells, an array of Th1-type cytokines along with certain growth factors like VEGF, KGF which are instrumental in the development of psoriasis. Moreover, ocular disorders are characterized by a series of interconnected cellular changes in the skin like hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils, and other types of leukocyte in the affected skin. Generally, ocular complications are managed with nonsteroidal anti-inflammatory drugs, corticosteroids, and immunosuppressive agents. Surgical therapy should be carried out, when there are chances of visual disturbance. Timely and correct diagnosis with quick treatment or referral to an ophthalmologist may prevent systemic and ocular disorders. This review highlights the association of psoriasis and ocular disorders with their clinical sign and symptoms.

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