Management of prostate cancer patients during COVID-19 pandemic

Öbek, Can; Doğanca, Tünkut; Argun, Ömer Burak; Kural, Ali Rıza

doi:10.1038/s41391-020-0258-7

Cited by 44 publications

(45 citation statements)

References 35 publications

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“…It needs to be admitted that in some cases, the laparoscopic and robotic surgeries bring a high risk of aerosol dispersal, since the circulated CO 2 and smoke may carry viral particles, including Coronavirus [ 71 ]. Some researchers recommended the restriction of robotic procedures considering the risk of aerosol generation [ [72] , [73] , [74] ]. Extra precautions were also recommended by the European Association of Urology (EAU) Robotic Urology Section (ERUS) [ 75 ].…”

Section: Robots In Covid-19mentioning

confidence: 99%

A literature survey of the robotic technologies during the COVID-19 pandemic

Wang

2021

Journal of Manufacturing Systems

190

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Since the late 2019, the COVID-19 pandemic has been spread all around the world. The pandemic is a critical challenge to the health and safety of the general public, the medical staff and the medical systems worldwide. It has been globally proposed to utilise robots during the pandemic, to improve the treatment of patients and leverage the load of the medical system. However, there is still a lack of detailed and systematic review of the robotic research for the pandemic, from the technologies’ perspective. Thus a thorough literature survey is conducted in this research and more than 280 publications have been reviewed, with the focus on robotics during the pandemic. The main contribution of this literature survey is to answer two research questions, i.e. 1) what the main research contributions are to combat the pandemic from the robotic technologies’ perspective, and 2) what the promising supporting technologies are needed during and after the pandemic to help and guide future robotics research. The current achievements of robotic technologies are reviewed and discussed in different categories, followed by the identification of the representative work’s technology readiness level. The future research trends and essential technologies are then highlighted, including artificial intelligence, 5 G, big data, wireless sensor network, and human-robot collaboration.

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Section: Robots In Covid-19mentioning

confidence: 99%

A literature survey of the robotic technologies during the COVID-19 pandemic

Wang

2021

Journal of Manufacturing Systems

190

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“…During the current COVID-19 pandemic, it is critical for clinicians to consider the impact of delayed RP for individual PCa patients [28]. COVID-19 should not result in missing the ideal time frame for treatment, especially in men with high-risk disease.…”

Section: Clinical Implications and Discussionmentioning

confidence: 99%

Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review

et al. 2021

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Purpose To summarize the available evidence on the survival and pathologic outcomes after deferred radical prostatectomy (RP) in men with intermediate- and high-risk prostate cancer (PCa). Methods The PubMed database and Web of Science were searched in November 2020 according to the PRISMA statement. Studies were deemed eligible if they reported the survival and pathologic outcomes of patients treated with deferred RP for intermediate- and high-risk PCa compared to the control group including those patients treated with RP without delay. Results Overall, nineteen studies met our eligibility criteria. We found a significant heterogeneity across the studies in terms of definitions for delay and outcomes, as well as in patients’ baseline clinicopathologic features. According to the currently available literature, deferred RP does not seem to affect oncological survival outcomes, such as prostate cancer-specific mortality and metastasis-free survival, in patients with intermediate- or high-risk PCa. However, the impact of deferred RP on biochemical recurrence rates remains controversial. There is no clear association of deferring RP with any of the features of aggressive disease such as pathologic upgrading, upstaging, positive surgical margins, extracapsular extension, seminal vesicle invasion, and lymph node invasion. Deferred RP was not associated with the need for secondary treatments. Conclusions Owing to the different definitions of a delayed RP, it is hard to make a consensus regarding the safe delay time. However, the current data suggest that deferring RP in patients with intermediate- and high-risk PCa for at least around 3 months is generally safe, as it does not lead to adverse pathologic outcomes, biochemical recurrence, the need for secondary therapy, or worse oncological survival outcomes.

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“…Docetaxel should be avoided. 29 EAU considers the treatment for metastatic castration-resistant (mCRPC) as a high priority. Thus, treatment with life-prolonging agents should be initiated in <6 weeks.…”

Section: Uro-oncological Surgeries During Covid-19 Pandemicmentioning

confidence: 99%

The Impact of COVID-19 Disease on Urology Practice

et al. 2021

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The diagnosis and timely treatment of cancer patients should not be compromised during an infectious disease pandemic. The pandemic of coronavirus disease 2019 (COVID-19) has serious implications on urology practice and raises particular questions for urologists about the management of different conditions. It was recommended to cancel most of the elective urological surgeries. Urological cancers surgeries that should be prioritized are radical cystectomy for selective tumors, orchiectomy for suspected testicular tumors, nephrectomy for c T3 + , nephroureterectomy for high-grade disease, and radical adrenalectomy for tumors >6 cm or adrenal carcinoma. Most prostatectomies can be delayed without compromising the survival rate of patients. Urological emergencies should be treated adequately even during this pandemic. There is a potential risk of coronavirus diffusion during minimally invasive procedures performed. It is crucial to use specific precautions when urologists performed those type of surgeries. It was also recommended to suspend the kidney transplantation program during the COVID-19 pandemic except for specific cases. In this review, we discussed the triage of urological surgeries, the risk of minimally invasive urological procedure, the kidney transplantation challenges, the systemic therapies, intravesical instillation of Bacillus Calmette-Guérin (BCG), endourology, teleconferencing, and telemedicine application in urology during the COVID-19 pandemic.

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Management of prostate cancer patients during COVID-19 pandemic

Cited by 44 publications

References 35 publications

A literature survey of the robotic technologies during the COVID-19 pandemic

A literature survey of the robotic technologies during the COVID-19 pandemic

Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review

The Impact of COVID-19 Disease on Urology Practice

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