2019
DOI: 10.1002/uog.20226
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Management of prenatally diagnosed spina bifida: how do we move ahead?

Abstract: https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/uog.20188 https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/uog.20136 https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/uog.20215

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(2 citation statements)
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“…It was calculated that to detect a 4% difference in neurodevelopmental impairment between the prenatal‐ and postnatal‐repair groups, with 80% power and 5% type‐1 error, 1886 patients per group would be needed 7 . This underscores the fact that available data are vastly underpowered to detect significant differences at this level 8 . There is also a lack of studies comparing neurocognitive outcome of children with spina bifida who undergo surgery and those who do not 7,8 .…”
Section: Introductionmentioning
confidence: 99%
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“…It was calculated that to detect a 4% difference in neurodevelopmental impairment between the prenatal‐ and postnatal‐repair groups, with 80% power and 5% type‐1 error, 1886 patients per group would be needed 7 . This underscores the fact that available data are vastly underpowered to detect significant differences at this level 8 . There is also a lack of studies comparing neurocognitive outcome of children with spina bifida who undergo surgery and those who do not 7,8 .…”
Section: Introductionmentioning
confidence: 99%
“…This underscores the fact that available data are vastly underpowered to detect significant differences at this level 8 . There is also a lack of studies comparing neurocognitive outcome of children with spina bifida who undergo surgery and those who do not 7,8 .…”
Section: Introductionmentioning
confidence: 99%