Management of Posterior Reversible Syndrome in Preeclamptic Women

Poma, Silvia; Delmonte, Maria Paola; Gigliuto, C.; Imberti, Roberto; Arossa, Alessia; Iotti, Giorgio

doi:10.1155/2014/928079

Cited by 12 publications

(16 citation statements)

References 27 publications

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“…Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder which is characterised by variable symptoms, which include visual disturbances, headache, vomiting, seizures and altered consciousness. 1 Its association is seen with a number of conditions including hypertension, pre-eclampsia and eclampsia, renal failure, systemic lupus erythematosus (SLE) and the use of some immunosuppressive agents. 2 3 PRES was first described in 1996 by Hinchey et al and shortly after the description, two other case series were published.…”

Section: Introductionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment

Parasher

Jhamb

2020

Postgraduate Medical Journal

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Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder which is characterised by variable symptoms, which include visual disturbances, headache, vomiting, seizures and altered consciousness. The exact pathophysiology of PRES has not been completely explained, but hypertension and endothelial injury seem to be almost always present. Vasoconstriction resulting in vasogenic and cytotoxic edema is suspected to be responsible for the clinical symptoms as well as the neuro-radiological presentation. On imaging studies, Symmetrical white matter abnormalities suggestive of edema are seen in the computer tomography (CT) and magnetic resonance imaging (MRI) scans, commonly but not exclusively in the posterior parieto-occipital regions of the cerebral hemispheres. The management is chiefly concerned with stabilization of the patient, adequate and prompt control of blood pressure, prevention of seizures and timely caesarean section in obstetric cases with pre-eclampsia/eclampsia. In conclusion, persistently elevated blood pressures remain the chief culprit for the clinical symptoms as well as the neurological deficits. Early diagnosis by diffusion weighted MRI scans, and differentiation from other causes of altered sensorium i.e. seizures, meningitis and psychosis, is extremely important to initiate treatment and prevent further complications. Although most cases resolve successfully and carry a favorable prognosis, patients with inadequate therapeutic support or delay in treatment may not project a positive outcome.

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Section: Introductionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment

Parasher

Jhamb

2020

Postgraduate Medical Journal

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“…Since symptoms of PRES may overlap with those of eclampsia and preeclampsia, a high degree of suspicion is required for early diagnosis and control of blood pressure. [ 8 ] Delay in diagnosis increases the morbidity as we observed in our case.…”

Section: Discussionmentioning

confidence: 50%

Posterior reversible leukoencephalopathy syndrome (PRES) in intensive care unit – Case series

Gokhale

Kimona

Kantor

et al. 2017

Indian Journal of Critical Care Medicine

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Introduction:Posterior reversible encephalopathy syndrome (PRES) is characterized by a range of clinico neuro radiological manifestation along with hypertension due to varied etiology. Contrary to its name, a small number of patients have residual neurological deficits. Patients with severe manifestation of PRES may get admitted to the Intensive Care Unit (ICU) due to coma or status epilepticus. Small case series and large multicenter studies have been reported.Materials and Methods:We report a single center series of ten cases admitted to ICU over a 5 year period in a tertiary care centre. We retrospectively analyzed patients, admitted to adult ICU with different etiologies, and diagnosed to have PRES. Outcome at discharge and at 90 days after ICU admission was noted.Result:The most common etiologies were medications. ICU admissions were mainly for uncontrolled hypertension, seizures, and low level of consciousness. All except one patient were ventilated. Four patients had residual neurological damage.Conclusion:Irrespective of the etiology, early control of blood pressure, and removal of precipitating factors is of paramount importance to prevent morbidity and mortality. Awareness about PRES among the intensivist is necessary to ensure early recognition and treatment.

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“…PRES or reversible posterior leukoencephalopathy syndrome [RPLS] is a rare cliniconeuroradiological entity associated with a number of conditions including preeclampsia, eclampsia, severely high blood pressure, renal failure, systemic lupus erythematosus, and the assumption of immunosuppressive agents [7]. Clinical features of PRES include headache, encephalopathy, seizures, cortical visual changes, and parietooccipital white matter edema visualized on neuroimaging modalities.…”

Section: Discussionmentioning

confidence: 99%

Exploring Neuropsychiatric Interphase in Perinatal Period – A Case Series

Gupta¹,

Dere²,

Mishra³

et al. 2019

Indian Journal of Mental Health

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Perinatal period spans from conception till one-year post-partum. Pregnancy and post-partum is characterised by significant biological changes in a woman's body including changes in blood pressure, blood volume, coagulability of blood and changes in immunity causing onset or relapse of certain medical and neurological conditions, which can face diagnostic and treatment challenges during this period. We aim to present a series of 3 cases which presented with psychiatric symptoms but on further evaluation were found to have neurological diagnosis-Cavernous Venous Thrombosis [CVT], Posterior Reversible Encephalopathy Syndrome [PRES] & Tuberculoma.

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Management of Posterior Reversible Syndrome in Preeclamptic Women

Cited by 12 publications

References 27 publications

Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment

Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment

Posterior reversible leukoencephalopathy syndrome (PRES) in intensive care unit – Case series

Exploring Neuropsychiatric Interphase in Perinatal Period – A Case Series

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