Management of Pediatric Facial Burns with Zinc-Hyaluronan Gel

Abstract

Zinc-hyaluronan-containing burn dressings have been associated with enhanced reepithelialization and low infection rates, although their effectiveness has not yet been investigated in pediatric facial thermal injuries. This single-arm, retrospective cohort study assessed the characteristics of 23 children (≤17-year-old) with facial superficial partial-thickness burns and the wound closure capabilities of the applied zinc-hyaluronan gel. Patients were admitted consecutively to the Pediatric Surgery Division in Pécs, Hungary, between 1 January 2016 and 15 October 2021. The mean age of the children was 6.2 years; 30.4% of them were younger than 1 year. An average of 3% total body surface was injured in the facial region and 47.8% of the patients had other areas damaged as well, most frequently the left upper limb (30.4%). The mean time until complete reepithelialization was 7.9 days and the children spent 2 days in the hospital. Wound cultures revealed normal bacterial growth in all cases and follow-up examinations found no hypertrophic scarring. In conclusion, pediatric facial superficial partial-thickness burns are prevalent during infancy and coincide with left upper limb injuries. Rapid wound closure and low complication rates are accountable for the moderate amount of hospitalization. These benefits, along with the gel’s ease of applicability and spontaneous separation, are linked to child-friendly burn care.

Intralesional Zinc Hyaluronate Injection to Prevent Keloid Recurrence After Surgical Excision: A Prospective, Randomized Pilot Study

“…4 The authors investigated a new method involving the use of intralesional zinc hyaluronate injection to prevent keloid scar recurrence after surgical excision and expected good results. 5 The authors' results indicate the nature of postsurgical keloid recurrence. In the first year after surgery, keloids did not develop, leading to incorrect conclusions of positive outcomes.…”