Management of patients suffering from hemorrhagic intracranial metastases: Propositions to help the neurosurgeon in emergency situations based on a literature review

Cardiac angiosarcoma with metastatic to lung, brain, and bone

“…Most cases of brain metastases from cardiac angiosarcoma are associated with hemorrhage, according to previous reports [ [11] , [28] , [29] , [30] , [31] , [32] ]. Hemorrhage occurs in 14% of typical brain metastases, and the rate of bleeding from angiosarcoma is remarkable [33] . Previous reports have shown that patients with brain metastases presented with headache and other neurological symptoms.…”

Contemplation of the Effect of Nivolumab Plus Cabosantinib Therapy on Cerebral Hemorrhage in Patients with Brain Metastasis of Renal Cell Carcinoma: A Case Report

“…Surgery for hematoma removal is required when conservative treatment is inadequate if compression findings are observed. Treatment decisions for hemorrhages caused by brain metastases should be made on a case-by-case basis for hemorrhage caused by brain metastases [ 24 ]. Cabozantinib is effective in patients with RCC and brain metastases but carries a risk of cerebral hemorrhage.…”

Unilateral arm weakness following retroperitoneal lymph node dissection for testicular germ cell tumour

“…In non‐seminomatous testicular germ cell tumours, spontaneous tumour bleed is rare, and while the patient's coagulation profile and platelets were normal, systemic immune response syndrome and immune suppression may have contributed to the bleeding risk. Systemic immune response syndrome may lead to increased metabolism and vascular complications, possibly influencing the occurrence of intratumoural bleeding [ 3 , 4 ].…”