Management of osteoporosis-related bone fractures: an integrated concept of care

Straßberger, C.; Unger, L.; Wéber, A.; Defèr, A.; Bonnaire, F.

doi:10.1007/s00402-009-0989-3

Cited by 6 publications

(3 citation statements)

References 23 publications

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“…There is a need for coordination of care to close this treatment gap to improve treatment rates as well as timing of osteoporosis treatment post-fracture to reduce future fractures effectively. Collaborations across orthopedic providers and payers and implementing an integrated model of care [40] may improve access and use of osteoporosis treatments in the US Medicare population.…”

Section: Discussionmentioning

confidence: 99%

Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population

et al. 2017

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SummaryOur aim was to evaluate the gap in osteoporosis treatment and the impact of osteoporosis treatment on subsequent fragility fractures. We found osteoporosis medication use lowered risk of subsequent fractures by 21% and that black race, higher CCI scores, dementia, and kidney diseases reduced the likelihood of osteoporosis medication use.IntroductionThe goal of this study was to evaluate the predictors of osteoporosis medication use and compare the risk of fragility fractures within 1 year of a fragility fracture between osteoporosis treated and untreated women.MethodsWe conducted a retrospective, observational cohort study using the national Medicare database. Elderly women (≥65 years) who were hospitalized or had an outpatient/ER service for fragility fracture between January 1, 2011 and December 31, 2011 were included. The outcomes of interest were the correlates of and time-to-osteoporosis medication use and risk of a subsequent fracture within 12 months for treated and untreated women. Cox regression was used to evaluate the predictors of treatment use and the risk of fracture based on treatment status.ResultsWomen (28,722) (27.7%) were treated with osteoporosis medication within 12 months of index fracture, and 74,979 (72.2%) were untreated. A number of patient characteristics were associated with a reduced likelihood of osteoporosis medication use, including black race, higher Charlson comorbidity index scores, presence of dementia, and kidney diseases in the baseline. The predictor most strongly and positively associated with osteoporosis medication use after fracture was osteoporosis medication use before fragility fracture (HR = 7.87; 95% CI 7.67–8.07). After adjusting for baseline characteristics, osteoporosis medication use lowered the risk of subsequent fractures by 21% (HR = 0.79, 95% CI 0.75–0.83) over 12 months compared to women without treatment.ConclusionsDemographics and clinical characteristics were strong predictors of osteoporosis medication use. In the US Medicare population, osteoporosis treatment significantly reduced the risk of fragility fractures.Electronic supplementary materialThe online version of this article (doi:10.1007/s00198-017-4072-6) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population

et al. 2017

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“…This program entitled “Osteoproactive” aimed to reduce consecutive osteoporotic fractures by providing multidisciplinary cooperation between different sectors of the health care system, improved diagnostics, optimized drug therapy as well as encouraging life style changes such as adequate nutrition and exercise. By these means, a reduction in osteoporosis‐associated costs was also aspired …”

Section: Introductionmentioning

confidence: 99%

Evaluation of a program of integrated care to reduce recurrent osteoporotic fractures

Goltz

Degenhardt

Maywald³

et al. 2013

Pharmacoepidemiology and Drug

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The program of integrated care was not found to be effective in reducing recurrent fractures. Cost effectiveness defined as a reduced rate of fractures in integrated care patients could not be shown by the assessed outcome measures. This missing reduction in fracture incidence may be explained by a non-sufficient improvement - compared to a placebo-controlled clinical trial - in medication supply and non-comparability of our real-world patient population with highly controlled clinical trial participants.

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“…As the older adult population increases, the incidence of osteoporosis and osteoporotic fractures have continued to increase 2,3). According to a recent study on osteoporosis in the Korean population, osteoporotic femoral neck fractures and accompanying mortality have increased 4)…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Prevalence of Osteoporosis and Proportion of Daily Protein Intake

Kim

Lee

et al. 2013

Korean J Fam Med

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BackgroundThe association between daily protein intake and osteoporosis is still controversial and only a few studies have explored the issue in Korea. This study investigated the relationship between daily protein intake and the prevalence of osteoporosis in Korean adults.MethodsThis study analyzed data extracted from the Korean National Health and Nutrition Examination Survey 4. Participants were aged 19 years or older and had never been treated for osteoporosis. The percentage of calories coming from protein intake was assessed by 24-hour recall method, and participants were divided into three groups according to recommended daily dietary protein intake as a proportion of total daily calories (i.e., <10%, 10%-20%, and >20%). A lumbar or femur neck bone mineral density T-score less than -2.5 was indicative of the presence osteoporosis. The influence of daily protein intake on the prevalence of osteoporosis was analyzed.ResultsIn both sexes, the group with the highest protein intake had significantly lower odds of developing lumber osteoporosis when compared to the group with the lowest protein intake, after adjusting for associated factors (females: odds ratio [OR], 0.618; 95% confidence interval [CI], 0.610 to 0.626; P for trend <0.001; males: OR, 0.695; 95% CI, 0.685 to 0.705; P for trend <0.001).ConclusionSufficient daily protein intake lowered the prevalence of osteoporosis in Korean adults. Further prospective studies are necessary to verify the preventive effect of adequate protein intake on osteoporosis.

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Management of osteoporosis-related bone fractures: an integrated concept of care

Cited by 6 publications

References 23 publications

Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population

Examining the treatment gap and risk of subsequent fractures among females with a fragility fracture in the US Medicare population

Evaluation of a program of integrated care to reduce recurrent osteoporotic fractures

The Relationship between Prevalence of Osteoporosis and Proportion of Daily Protein Intake

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