Management of oral leukoplakia: a position paper of the Society of Oral Medicine, Chinese Stomatological Association

Abstract

Objective. The objective of this study was to develop the first edition of a Chinese evidence-based position paper on the management of oral leukoplakia (OLK). Study Design. The consultant group for drafting the position paper consisted of 31 oral medicine specialists and 2 evidence-based medicine specialists. English studies (searched in PubMed, EMBASE, and the Cochrane Library) and Chinese studies (searched in China National Knowledge Infrastructure and WanFang) published before January 2018 were used. The quality of the study was assessed using the Grading of Recommendations Assessment, Development, and Evaluation grid, and the strength of the recommendations was determined based on the results of 3 rounds of voting among the consultant group members using the Delphi method. Results. Twenty-two evidence-based guidelines for clinical management and monitoring of OLK were established in this position paper. A clinical path diagram for oral health practitioners was constructed based on the recommendations. Conclusion. Current evidence suggests that management and monitoring of patients with OLK should be performed by experienced clinicians to control the lesion and for early detection of malignant transformation. However, all recommendations are based on evidence of low or extremely low quality and may require further modification as new evidence is produced. (Oral Surg Oral Med Oral Pathol Oral Radiol 2021;000:1À12)

How ChatGPT performs in Oral Medicine: The case of oral potentially malignant disorders

“…We started by selecting guidelines and consensus documents disseminated by reputable scientific societies on the definition, classification, diagnosis, evaluation, malignant transformation and management of OPMDs (Birur et al, 2022; Chen et al, 2021; Lingen et al, 2017; Stojanov & Woo, 2018; Warnakulasuriya et al, 2021). Based on these statements, we formulated a series of “primary questions” that were entered into ChatGPT (version 23 of March 2023) using the function “New chat”.…”

“…We started by selecting guidelines and consensus documents disseminated by reputable scientific societies on the definition, classification, diagnosis, evaluation, malignant transformation and management of OPMDs (Birur et al, 2022;Chen et al, 2021;Lingen et al, 2017;Stojanov & Woo, 2018;Warnakulasuriya et al, 2021).…”

Histopathological Assessment of Oral Leukoplakia Among Snuff Users and Non-Users

“…Epithelial dysplasia is considered a marker of the conversion of a lesion into malignancy. [3][4][5][6][7][8] Tobacco use is among one the etiological factors of oral leukoplakia. 9,10 .…”

Novel tetrahydrocurcumin integrated mucoadhesive nanocomposite κ-carrageenan/xanthan gum sponges: a strategy for effective local treatment of oral cancerous and precancerous lesions

“…The main treatments for OSCC are surgery, radiotherapy, and chemotherapy, either alone or in combination (Nandini et al., 2020 ). Whereas, OPL has a number of treatment options including drug therapy, surgery, and laser ablation; none of them are curative (Chen et al., 2021 ). Therefore, continued research for safer and more efficient chemoprevention and treatment is clearly needed to improve efficiency and reduce treatment costs (H. Wang et al., 2012 ).…”