Management of metastatic vertebral lesions by interventional techniques: Systematic review of outcomes

Abstract

Vertebral metastases represent an important cause of cancer-related morbidity and mortality. Among all available treatments, interventional percutaneous techniques have recently emerged as potential strategies for the management of oncologic patients with vertebral lesions. Minimally invasive image-guided therapies include “ablative” and “consolidative” ones. According to the number of metastases and the patient's performance status, ablative techniques can be performed with a curative or a palliative purpose since necrosis induced by critic changes of intralesional temperature determines both tumor debulking and destruction of pain receptors. On the other hand, consolidative treatments are based on the injection of polymethylmethacrylate cement to improve structural vertebral integrity and obtain pain alleviation and prevention of skeletal-related events. This article reviews the current recommendations supporting the role of interventional radiology in the management of vertebral metastases, focusing on the last updates in literature.

A comparative study of establishing rabbit vertebral tumor model by two ways of CT-guided percutaneous puncture

“…However, rapid ablation at high power can cause nerve damages [ 3 , 9 ]. Percutaneous vertebroplasty (PVP) is to inject bone cement (PMMA) into the diseased vertebral body to reconstruct the physiological curvature of the patient's spine under the guidance of imaging, so as to enhance the stability of the spine [ 10 , 11 ]. After more than 20 years of development, it has become a reliable method for the treatment of vertebral hemangioma, osteoporotic vertebral compression fracture and vertebral malignant tumor.…”