Management of malignant pleural effusion with different pleural catheters

Karapolat, Sami; Buran, Alaaddin; Tekinbaş, Celal

doi:10.4103/lungindia.lungindia_173_17

Cited by 2 publications

(3 citation statements)

References 3 publications

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“…[ 1 – 3 ] Most MPEs are secondary to metastases to the pleura from other sites, most commonly lung and breast, which together cause 50% to 65% of all MPE. [ 4 , 5 ] Breathlessness, dyspnea and other symptoms often seriously distress and affect the quality of life (QOL). [ 4 – 7 ]…”

Section: Introductionmentioning

confidence: 99%

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The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion

Zhang

Jiang²,

Gao³

et al. 2021

Medicine

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Background: Malignant pleural effusion (MPE) is one of the commonest causes of an exudative pleural effusion. Breathlessness, dyspnea and other symptoms often seriously distress and affect the quality of life. The external application of mirabilite and rhubarb (EAMR) combined with intrathoracic infusion of cisplatin, as an alternative treatment for MPE, is popular in China. The study aims to assess its effectiveness and safety combined with intrathoracic chemotherapy. Methods: This study is a prospective, randomized controlled clinical trial. Patient visits were performed at baseline and days 14 and 28 after treatment. Clinical outcomes were measured after chest drain placement using the criterion of efficacy refer to WHO standard, and QLQ-C30 questionnaire. Results: Database records of patients treated in our institution for MPE between October, 2016 and March, 2019. The study included 84 eligible patients. They were categorized with a randomization schedule into treatment group (N = 42) and control group (N = 42). There is statistical significance in the comparison of the total effective rate between these 2 groups (66.67% vs 54.76%, P < .05). Furthermore, there is statistical significance in the comparison of items of Physical (1.95 ± 0.50 vs 2.19 ± 0.58%, P < .05), Pain (1.98 ± 0.42 vs 2.07 ± 0.32, P < .05), and Global Health (1.23 ± 0.64 vs 1.13 ± 0.23%, P < .05) between these 2 groups. None of the patients had adverse reactions such as skin allergy and chest tightness. Conclusions: The total effective rate of treatment group using extra external application of mirabilite rhubarb powder is significantly higher than that of control group. The improvement of patients’ clinical symptoms is greater in treatment group and no adverse reactions is found. Therefore, external application of mirabilite and rhubarb combined with intrathoracic infusion of cisplatin is an effective method for the treatment of MPE, which is worth popularizing.

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Section: Introductionmentioning

confidence: 99%

“…[ 4 , 5 ] Breathlessness, dyspnea and other symptoms often seriously distress and affect the quality of life (QOL). [ 4 – 7 ]…”

Section: Introductionmentioning

confidence: 99%

The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion

Zhang

Jiang²,

Gao³

et al. 2021

Medicine

View full text Add to dashboard Cite

show abstract

“…Breathlessness, dyspnea and other symptoms often seriously distress and affect the quality of life (QOL). [ 4 – 7 ]…”

Section: Introductionmentioning

confidence: 99%

The clinical efficacy of traditional Chinese medicine in the treatment of malignant pleural effusion

Lin

Jiang²,

Gao³

et al. 2020

Medicine

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Background: The objective of this meta-analysis was to summarize and identify the available evidence from studies to estimate the clinical value of traditional Chinese medicine (TCM) in the treatment of malignant pleural effusion (MPE). And provides clinicians with evidence on which to base their clinical decision making. Methods: This review will include all studies comparing clinical efficacy of TCM in the treatment of MPE. The search strategy will be performed in 9 databases. We will not establish any limitations to language and publication status, published from inception to the July, 2020. Two reviewers will screen, select studies, extract data, and assess quality independently. Outcome is clinical efficacy, QLQ-C30 questionnaire and safety. The methodological quality including the risk of bias of the included studies will be evaluated. We will carry out statistical analysis using RevMan 5.3 software. Results: This study will summarize current evidence to assess the efficacy and safety of TCM in the treatment of MPE. Conclusion: The findings of this study will provide helpful evidence for the clinician, and will promote further studies, as well as studying the value of TCM.

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Management of malignant pleural effusion with different pleural catheters

Cited by 2 publications

References 3 publications

The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion

The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion

The clinical efficacy of traditional Chinese medicine in the treatment of malignant pleural effusion

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