2007
DOI: 10.1007/s11864-007-0023-3
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Management of Locally Advanced Non Small Cell Lung Cancer from a Surgical Perspective

Abstract: Stage III, locally advanced NSCLC, represents an incredibly heterogeneous group of patients. Optimal therapy for this group is controversial and the role of surgery is not clearly defined. There have been several randomized trials over the past three decades that have helped to guide our decision-making. In patients with T3N1 tumors, surgery is the primary treatment and there is now evidence for the use of adjuvant chemotherapy. Consensus has shown that the majority of IIIB tumors are not amenable to resection… Show more

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Cited by 15 publications
(12 citation statements)
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“…Önceki evrelemeye göre bu tümörlerin cerrahi rezeksiyon şansı bulunmamaktadır. Bununla beraber güncel yaklaşımda bu tümörlerin çoğuna cerrahi rezeksiyon yapılmış ve elde edilen sonuçlar uzak metastazı olanlara göre oldukça iyi bulunmuştur [41][42][43][44] Bu cerrahi sonuçlar 7. sürüm evreleme sistemindeki deği-şiklikleri destekler niteliktedir.…”
Section: Evreleme Temelli Tedavi Seçenekleriunclassified
“…Önceki evrelemeye göre bu tümörlerin cerrahi rezeksiyon şansı bulunmamaktadır. Bununla beraber güncel yaklaşımda bu tümörlerin çoğuna cerrahi rezeksiyon yapılmış ve elde edilen sonuçlar uzak metastazı olanlara göre oldukça iyi bulunmuştur [41][42][43][44] Bu cerrahi sonuçlar 7. sürüm evreleme sistemindeki deği-şiklikleri destekler niteliktedir.…”
Section: Evreleme Temelli Tedavi Seçenekleriunclassified
“…6-9 Multiple tumors of similar histology in the same lobe are now T3 instead of T4 (provided that none of the individual lesions meets T4 criteria on its own). Likewise, patients with histologically similar tumor nodules found in separate lobes of the same (ipsilateral) lung are now staged as T4 (previously M1).…”
Section: Tnm Staging Changes New To the 7th Editionmentioning
confidence: 99%
“…Among stage IIIA non-small cell lung cancer patients, T4N0-1 cases can be good candidates for surgery and have a relatively favorable postoperative prognosis [1, 2]. However, most T4 cases with thoracic vertebral invasion may not be operated as complete resection with vertebrectomy is challenging [2].…”
Section: Introductionmentioning
confidence: 99%
“…However, most T4 cases with thoracic vertebral invasion may not be operated as complete resection with vertebrectomy is challenging [2]. …”
Section: Introductionmentioning
confidence: 99%