Management of Hyperacute Amiodarone-induced Pulmonary Toxicity

Abstract

One of the major complications of amiodarone therapy is acute pulmonary toxicity (APT). Patients tend to have amiodarone-induced toxicity after Coronary Artery Bypass Surgery (CABG). For this reason, priority should be given to the treatment of this fatal complication. Acute pulmonary toxicity due to amiodarone is a treatable phenomenon if diagnosed at an early stage, for this reason, meticulous follow-up and suspicion are of great importance. We presented the treatment of a 72-year-old male who underwent 4-vessel coronary artery bypass grafting surgery but developed amiodarone-induced pulmonary toxicity immediately after amiodarone infusion.

Acute Cardiovascular and Cardiorespiratory Effects of JWH-018 in Awake and Freely Moving Mice: Mechanism of Action and Possible Antidotal Interventions?

“…Amiodarone induced tachypnea administered by itself, but also reverted JWH-018-induced bradypnea. This is consistent with clinical cases, which reported tachypnea after amiodarone assumption [69,70].…”