Management of Healthcare Workers with Pharyngitis or Suspected Streptococcal Infections

Weber, David J.; Rutala, William A.; Denny, Floyd W.

doi:10.2307/30141550

Cited by 17 publications

(1 citation statement)

References 78 publications

(44 reference statements)

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“…The proportion of infections that were nosocomially acquired is of concern. Invasive GAS infection in health care settings can be highly transmissible 25 and is associated with an increased risk of a fatal outcome; 26 , 27 institutional outbreaks are not uncommon 28 . In the US, it is recommended that one nosocomial postpartum or postsurgical invasive GAS infection should initiate enhanced surveillance and two or more should prompt an epidemiological investigation that includes carriage studies of health care workers 29 .…”

Section: Discussionmentioning

confidence: 99%

The epidemiology of invasive group A streptococcal disease in Victoria, Australia

O’Grady

Kelpie

Andrews

et al. 2007

Medical Journal of Australia

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Objective: To estimate the incidence and severity of invasive group A streptococcal infection in Victoria, Australia. Design: Prospective active surveillance study. Setting: Public and private laboratories, hospitals and general practitioners throughout Victoria. Patients: People in Victoria diagnosed with group A streptococcal disease notified to the surveillance system between 1 March 2002 and 31 August 2004. Main outcome measure: Confirmed invasive group A streptococcal disease. Results: We identified 333 confirmed cases: an average annualised incidence rate of 2.7 (95% CI, 2.3–3.2) per 100 000 population per year. Rates were highest in people aged 65 years and older and those younger than 5 years. The case‐fatality rate was 7.8%. Streptococcal toxic shock syndrome occurred in 48 patients (14.4%), with a case‐fatality rate of 23%. Thirty cases of necrotising fasciitis were reported; five (17%) of these patients died. Type 1 (23%) was the most frequently identified emm sequence type in all age groups. All tested isolates were susceptible to penicillin and clindamycin. Two isolates (4%) were resistant to erythromycin. Conclusion: The incidence of invasive group A streptococcal disease in temperate Australia is greater than previously appreciated and warrants greater public health attention, including its designation as a notifiable disease.

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Section: Discussionmentioning

confidence: 99%