Management of frey syndrome

Bree, Remco de; Waal, I. van der; Leemans, C. René

doi:10.1002/hed.20568

Cited by 102 publications

(103 citation statements)

References 43 publications

(41 reference statements)

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“…Hastalara özellikle çiğneme sonrası terleme olup olmadığı sorgulandığın-da ise yaklaşık %30-40 hastada bu semptomlara rastlanmaktadır. Ek olarak tanısal testlerle bakıldığında parotidektomi sonrası %95 oranında ilgili semptomlara rastlanmıştır (7,21) . Çalışmamızda, hastalar ortalama 21,7 ay takip edilmiş olup, Frey Sendromu literatürle karşı-laştırıldığında benzer oranlarda tespit edilmiştir.…”

Section: Discussionunclassified

Warthin’s Tumour of Parotid Gland: Post-Surgical Evaluation of Follow-up and Treatment

Kozcu¹,

Arslan²,

Uluyol³

et al. 2017

Terh

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ÖZAmaç: Bu çalışmanın amacı, parotis bezi Warthin tümörü olan hastaları retrospektif olarak inceleyerek, hastaların demografik ve klinik özelliklerini, uygulanan cerrahi tedavi sonuçlarını ve nüks durumlarını tanımlamaktır. Yöntemler: Temmuz 2008 ile Ağustos 2014 tarihleri arasında parotis bezi Warthin tümörü nedeniyle opere edilen kırk bir hasta çalışmaya dahil edildi. Hastaların demografik özellikleri, operasyon şekli, takip süresi, çift taraflılık ve cerrahi tedavi sonrası nüks durumu kaydedildi. Takipte bütün hastalara kontrastlı manyetik rözen-ans görüntüleme uygulandı. Bulgular: Çalışmaya dahil edilen hastalar 40 ile 81 yaş arasındaydı (ortalama yaş 57,9). Erkek kadın oranı 4,8:1 idi. Kırk bir hastanın yedisinde çift taraflı Warthin tümörü saptandı. Kırk üç yüzeyel parsiyel parotidektomi ve üç total parotidektomi uygulandı. Çift taraflı tümörü olan hastalardan ikisi tedaviyi reddetmesi üzerine diğer taraftan cerrahi yapılmadı. Cerrahi sonrası hastalar ortalama 21,7 ay takip edildi, iki hastada nüks saptandı. Sonuç: Uzun dönem nüks riski göz önüne alındığında yüzeyel parsiyel parotidektominin yüzeyel lob yerleşimli Warthin tümörlerinde uygun tedavi yöntemi olduğu görüldü.Anahtar kelimeler: Warthin tümörü, yüzeyel parsiyel parotidektomi, nüks, takip ABSTRACT Objective: The aim of this study is to describe patients' demographic and clinical features, results of applied surgical treatment and recurrence status by retrospectively investigating the patients with Whartin`s tumor of parotis gland. Methods: Forty-one patients who were operated between July 2008 and August 2014 because of Warthin's tumour of parotid gland were included in the study. Patients' demographic features, operation type, follow-up time, bilaterality and recurrence status after surgical treatment were noted. Magnetic resonance imaging with contrast was implemented to all patients during follow-up. Results: The patients aged between 40 and 81 years (median age, 57.9) were included in the study. Male/female ratio was 4,8:1. Bilateral Warthin's tumours were detected in seven of the forty-one patients. Forty-three superficial partial parotidectomies and three total parotidectomies were performed. Contralateral surgeries were not performed in 2 patients with bilateral tumors who refused surgical treatment. The patients were followed up for a median of 21.7 months after surgery. The disease recurred in two patients. Conclusion: Superficial partial parotidectomy was established as a suitable treatment modality with Warthin's tumours localized in superficial lobe when the long-term risk of recurrence was taken into consideration.

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Section: Discussionunclassified

Warthin’s Tumour of Parotid Gland: Post-Surgical Evaluation of Follow-up and Treatment

Kozcu¹,

Arslan²,

Uluyol³

et al. 2017

Terh

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“…According to the literature, the incidence of Frey syndrome showed great variation, ranging from 2.6 to 97.6% [6], which could be explained by the different study designs, variable investigation periods with different diagnostic standards (e.g., objective testing [i.e., starch-iodine test] or the presence of clinical symptoms), and different surgical techniques. The presumed pathophysiology of Frey syndrome was that aberrant parasympathetic nerve outgrowth to the overlying sweat glands of the face caused the symptoms of sweating and flushing in association with eating [19,20]. Several prophylactic techniques based on the presumed pathophysiology have been proposed with the aim to place a barrier between the postganglionic parasympathetic nerve fibers and the sweat glands of the skin flap while at the same time preventing the connection in between [20,21].…”

Section: Discussionmentioning

confidence: 99%

Comparing Modified with Conventional Parotidectomy for Benign Parotid Tumors

Gao

Ren²,

Li³

et al. 2017

ORL

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Purpose: We conducted a study to compare the functional outcomes and surgical complications of patients with benign parotid tumors treated with conventional parotidectomy and modified parotidectomy. Methods: This study retrospectively analyzed 99 patients who had benign parotid lesions and underwent parotidectomy using either conventional or modified parotidectomy. The operation time, cosmetic outcome, great auricular nerve anesthesia, incidence of Frey syndrome, and secretory function with the two techniques were compared. Results: The mean operation time was shorter and the total complication rate was obviously lower in the modified surgery group (p < 0.001). In the modified surgery group, the incision was more cosmetic (p < 0.001), the sensory deficit rate was low (p < 0.001), and the sensory recovery rate was high, and transient facial paralysis and Frey syndrome were rare. Furthermore, glandular function was preserved in patients with a conserved Stensen duct. There was no tumor recurrence in the two groups during a mean follow-up of 29.8 months. Conclusion: Modified surgical techniques for benign parotid neoplasms significantly reduced the surgery time and improved the surgery outcomes compared with the conventional approach. This adds to the evidence to support the effectiveness of modified parotidectomy in selected patients with benign parotid tumors.

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“…It is reported that around 10% of patients undergoing parotidectomy will complain of gustatory sweating, however, on questioning, 30-40% will reply that they experience it, while it can be demonstrated objectively by starch-iodine test in 95% of patients. 8 The pathophysiology of this syndrome was described by Andre Thomas 9 in 1927 and later by Ford and Woodhall 10 in 1938. They postulated that Frey's syndrome is caused by aberrant regeneration of sectioned postganglionic parasympathetic fibers that are severed during parotidectomy.…”

Section: Surgical Technique Of Fascia Lata Interpositionmentioning

confidence: 99%