Management of fever in patients with central vein catheters

Prince, Alice; Heller, B.; Levy, Joseph M.; Heird, William C.

doi:10.1097/00006454-198601000-00004

Cited by 57 publications

(13 citation statements)

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“…It is important to note that these patients had severe weight loss prior to the institution of HPN and each died from a disease diagnosed before parenteral nutrition was started. Patient number 7 died from Burkitt's lymphoma, number 9 from liver tuberculosis, number 16 No measurements were performed of either body composition or indirect calorimetry in this retrospective study, but the fact that those patients who did gain weight continued to increase in weight until they reached preillness levels suggests that this phenomenon is related to increases in lean body mass and not in extracellular water. Furthermore, in other related studies, our group has followed resting energy expenditure and body composition in AIDS patients receiving TPN (unpublished data); the results of these investigations indicate that the increase in weight is not related to extracellular water.…”

Section: Resultsmentioning

confidence: 86%

Risks and Benefits of Home Parenteral Nutrition in the Acquired Immunodeficiency Syndrome

Singer

Rothkopf

Kvetan

et al. 1991

J Parenter Enteral Nutr

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The gastrointestinal tract is a major target of the human immunodeficiency virus. Many AIDS patients have weight loss and/or diarrhea. Parenteral nutrition can be used to treat malnutrition associated with malabsorption. We reviewed retrospectively the clinical course of 22 patients with AIDS and weight loss greater than 10% who received home parenteral nutrition (HPN) for 56.2 patient-months. Mean weight loss was 21.4%, mean duration of HPN 2.55 months, mean age 37.4 years. Fifteen patients gained weight, six stabilized and two continued to lose weight. Nine patients returned to previous activity. Five died. The rates of catheter-related sepsis, complications, and metabolic disturbances were 0.12, 0.25, and 0.12/100 catheter days, respectively, results identical to those reported in other patient populations where HPN is commonly applied. We found that HPN induced weight gain and clinical improvement in most patients without higher risks of sepsis than in patients with malignancies.

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Section: Resultsmentioning

confidence: 86%

Risks and Benefits of Home Parenteral Nutrition in the Acquired Immunodeficiency Syndrome

Singer

Rothkopf

Kvetan

et al. 1991

J Parenter Enteral Nutr

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“…3,4,20 Initial published literature on the use of antimicrobial therapy alone to clear CLABSI in pediatrics is limited and appears to have inflated positive results because of the exclusion of fungal BSIs, small sample sizes, and variable success definitions. 26,27 However, few published reports in the past 2 decades studied various catheter salvage interventions versus control groups receiving systemic antimicrobial therapy alone in both pediatric and adult patients. 6,7,9,10 These control group success rates varied from 32% to 66%, and, additionally in the report by Dannenburg et al, 2 infection cleared in 47% of CLABSI controls treated with antimicrobial therapy alone.…”

Section: Discussionmentioning

confidence: 99%

Short-Dwell Ethanol Lock Therapy in Children Is Associated With Increased Clearance of Central Line–Associated Bloodstream Infections

McGrath

Salloum

Chen

et al. 2011

Clin Pediatr (Phila)

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“…The results of a number of studies of children have suggested that some catheter-related infections may be cleared by antimicrobial therapy alone, and that the CVC need not be removed in up to 75% of cases [67,68,69,70,71,72,73]. Furthermore, although there have been anecdotal reports of the cure of fungemia without catheter removal, the treatment of CVC-associated fungemia while retaining the catheter has a low success rate and may be associated with a higher mortality [8].…”

Section: Catheter Replacementmentioning

confidence: 99%

Catheter-related infections in children treated with hemodialysis

et al. 2004

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Infectious complications of the central venous catheter (CVC) are a major source of morbidity among children treated with hemodialysis (HD), with catheter-related bloodstream infections (CRBSI) being the most important clinical manifestations. As only a few studies of children on HD have been published, the management of CVC-related infections in this population is mainly based on data derived from adults or occasionally from children not affected by end-stage renal disease (ESRD). The aim of this review is to discuss current knowledge concerning the epidemiology, prevention, and treatment of catheter-related infections in children on HD. Catheters impregnated with antibiotics/antiseptics, lock antibiotic prophylaxis, nasal mupirocin, and the application of ointments at the exit-site have all been proposed as means of reducing the risk of CVC infections, but their real efficacy in the pediatric population has not yet been demonstrated. Furthermore, it is not clear how long antibiotic therapy should be continued, and there is still debate as to whether the catheter has to be removed. We propose some practical guidelines for the management of CRBSI in children with percutaneously inserted and surgically implanted HD catheters, but a number of unresolved clinical issues still remain, which will require prospective clinical trials specifically performed in pediatric patients with ESRD.

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Management of fever in patients with central vein catheters

Cited by 57 publications

References 0 publications

Risks and Benefits of Home Parenteral Nutrition in the Acquired Immunodeficiency Syndrome

Risks and Benefits of Home Parenteral Nutrition in the Acquired Immunodeficiency Syndrome

Short-Dwell Ethanol Lock Therapy in Children Is Associated With Increased Clearance of Central Line–Associated Bloodstream Infections

Catheter-related infections in children treated with hemodialysis

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