Management of dermatologic adverse events associated with tumor treating fields in patients with glioblastoma multiforme: A 27-case series

Chen, Xiaoxue; Zhang, Yihong; Zhao, Qinqin; Chen, Lan Bai Xiaoqun; Zhou, Zhihuan

doi:10.1016/j.apjon.2022.100095

Cited by 1 publication

(1 citation statement)

References 26 publications

(41 reference statements)

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“…The most common side effect noted in the EFT treated group was scalp irritation associated with the transducer arrays, where moderate irritation was observed in 52% of the patients and severe irritation in 2% [ 98 ]. However, a later study of 27 patients in Southern China reported dermatologic adverse events in as many as 82% of the patients [ 119 ]. One possible explanation for the increased incidence of dermatological issues could be the heat of the tropical climate in that region.…”

Section: Medical Devices Used To Deliver Novel Anti-tumour Therapeuti...mentioning

confidence: 99%

Medical Device Advances in the Treatment of Glioblastoma

Foo

Munir²,

Kumaria

et al. 2022

Cancers

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Despite decades of research and the growing emergence of new treatment modalities, Glioblastoma (GBM) frustratingly remains an incurable brain cancer with largely stagnant 5-year survival outcomes of around 5%. Historically, a significant challenge has been the effective delivery of anti-cancer treatment. This review aims to summarize key innovations in the field of medical devices, developed either to improve the delivery of existing treatments, for example that of chemo-radiotherapy, or provide novel treatments using devices, such as sonodynamic therapy, thermotherapy and electric field therapy. It will highlight current as well as emerging device technologies, non-invasive versus invasive approaches, and by doing so provide a detailed summary of evidence from clinical studies and trials undertaken to date. Potential limitations and current challenges are discussed whilst also highlighting the exciting potential of this developing field. It is hoped that this review will serve as a useful primer for clinicians, scientists, and engineers in the field, united by a shared goal to translate medical device innovations to help improve treatment outcomes for patients with this devastating disease.

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Section: Medical Devices Used To Deliver Novel Anti-tumour Therapeuti...mentioning

confidence: 99%