“…If present, the external opening can be found over the anterior border of the sternocleidomastoid muscle, between the middle and lower third. (13,14) In theory, fourth branchial arch anomalies follow a more convoluted route than third branchial arch anomalies. The former originate from the apex of the pyriform sinus medial to the superior laryngeal nerve, and travel inferiorly in the tracheoesophageal groove, behind the thyroid gland and parallel to the recurrent laryngeal nerve into the mediastinum, where they loop around the aorta on the left and subclavian artery on the right.…”