Management of Chronic Respiratory Failure in Chronic Obstructive Pulmonary Disease: High-Intensity and Low-Intensity Ventilation

Orr, Jeremy E.; Azofra, Ana Sánchez; Tobias, Lauren

doi:10.1016/j.jsmc.2020.08.007

Cited by 2 publications

(2 citation statements)

References 74 publications

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“…There is not only one criterion for indicating long-term NIV in COPD, which is confirmed by common practice that patients need to be approached individually [7,9,44,66]. Long-term NIV may be indicated at a stable stage of COPD or after overcoming an acute exacerbation, meeting specific criteria, and considering the patient's needs.…”

Section: Indications For Niv In Chronic Hypercapnic Respiratory Failure In Copdmentioning

confidence: 99%

“…Because patients with COPD form a wide range of different phenotypes, making precise recommendations on setting long-term NIV is not easy. In recent years, various approaches have been used, including the so-called low-intensity NIV (LI-NIV) and high-intensity NIV (HI-NIV) [44,66]. The main difference is that HI-NIV uses higher values of IPAP and backup frequency to achieve normocapnia [48].…”

Section: Management Of Long-term Nivmentioning

confidence: 99%

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Ventilation Strategies in Obese Patients

Pobeha¹

2022

Mechanical Ventilation

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Obesity is an increasingly prevalent disease and is a root and complication of conditions necessitating mechanical ventilation. Obese patients require a careful approach due to the particular manner of how ventilatory mechanics is affected, if obstructive sleep apnea (OSA) is present. The two main diagnoses we may encounter while ventilating these patients are obesity hypoventilation syndrome (OHS) and chronic obstructive pulmonary disease (COPD) in an obese patient, which has been recently proposed as a novel phenotype of COPD. The excessive amount of fat in the abdomen, chest wall, and around upper airways warrants the use of special ventilation modes and settings. This chapter provides insight into which issues should be considered when ventilating an obese patient, either in acute or chronic conditions. We stress the importance of acknowledging the high risk of OSA and how OSA affects the ventilation algorithms.

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Section: Indications For Niv In Chronic Hypercapnic Respiratory Failure In Copdmentioning

confidence: 99%

Section: Management Of Long-term Nivmentioning

confidence: 99%

Ventilation Strategies in Obese Patients

Pobeha¹

2022

Mechanical Ventilation

View full text Add to dashboard Cite

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Study of the flow mechanism and influencing factors of sputum excretion from the distal lung

Jin

Cui

Chen

et al. 2022

HFF

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Purpose The purpose of this paper is to study the mechanism of efficient sputum excretion from the distal lung by using a tessellationally distal lung model with alveolar pores. Design/methodology/approach First, a two-dimensional tessellational composite structure of the bronchus, alveoli and alveolar pores (Kohn pore) is constructed with the tessellational splitting and fusion of regular hexagonal elements. Then, the level set method is used to study the effects of alveolar pores and their sizes, expiratory cycles and respiratory intensity. Findings The existence of alveolar pores is the prerequisite for sputum excretion, and there is an optimal size of alveolar pores for sputum excretion. Strong asymmetric respiration can break the reversibility of the flow at a low Reynolds number and causes significant net displacement of sputum. The expiratory cycle is negatively correlated with the net displacement of sputum. The respiratory intensity is positively correlated with the net displacement of sputum. Originality/value This research is helpful for understanding the complex sputum excretion process in diseases, such as pneumonia, and developing corresponding adjuvant therapy.

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Management of Chronic Respiratory Failure in Chronic Obstructive Pulmonary Disease: High-Intensity and Low-Intensity Ventilation

Cited by 2 publications

References 74 publications

Ventilation Strategies in Obese Patients

Ventilation Strategies in Obese Patients

Study of the flow mechanism and influencing factors of sputum excretion from the distal lung

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