Management of Chronic Photosensitive Eczema

Yokel, Benjamin K.; Hood, Antoinette F.; Morison, Warwick L.

doi:10.1001/archderm.1990.01670340033003

Cited by 13 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found no comparative studies using PUVA in the treatment of CAD. There are a limited number of case reports and small case series reporting the use of PUVA in CAD …”

Section: Psoralen–ultraviolet a For Specific Dermatosesmentioning

confidence: 99%

“…PUVA phototherapy is generally undertaken under close supervision under cover of topical or systemic corticosteroid, as discussed above . Maintenance treatment may be required.…”

Section: Psoralen–ultraviolet a For Specific Dermatosesmentioning

confidence: 99%

“…There are a limited number of case reports and small case series reporting the use of PUVA in CAD. [106][107][108][109][110][111][112] The largest case series (only four patients) reported the use of PUVA with topical corticosteroid cover and inpatient supervision in UV-protected rooms (first dose was 0Á25 J cm À2 , with increments of 0Á25-2Á50 J cm À2 , twice a week; maintenance at 10 J cm À2 fortnightly, then monthly). After each of the first six exposures, topical betamethasone or hydrocortisone butyrate was applied immediately to the trunk and 1% hydrocortisone to the face.…”

Section: When Should Psoralen-ultraviolet a Be Used In Preference To mentioning

confidence: 99%

“…108,109 Treatment with PUVA covered with oral prednisolone and initial inpatient supervision has been reported in three case reports. 111,112 Prednisolone (60-100 mg) was administered daily initially and tapered over 4 weeks, while PUVA was given 3-4 times a week initially and tapered to once or twice weekly. Maintenance PUVA was given for 6-18 months.…”

Section: When Should Psoralen-ultraviolet a Be Used In Preference To mentioning

confidence: 99%

“…78,83,85,88 Chronic actinic dermatitis PUVA phototherapy is generally undertaken under close supervision under cover of topical or systemic corticosteroid, as discussed above. 108,109,111,112 Maintenance treatment may be required. Annual repeated courses can be considered but the benefit needs to be balanced against the long-term risk of skin carcinogenicity.…”

Section: What Special Precautions Should Be Undertaken During Psoralementioning

confidence: 99%

See 4 more Smart Citations

British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of psoralen–ultraviolet A therapy 2015

et al. 2016

View full text Add to dashboard Cite

“…We found no comparative studies using PUVA in the treatment of CAD. There are a limited number of case reports and small case series reporting the use of PUVA in CAD …”

Section: Psoralen–ultraviolet a For Specific Dermatosesmentioning

confidence: 99%

“…PUVA phototherapy is generally undertaken under close supervision under cover of topical or systemic corticosteroid, as discussed above . Maintenance treatment may be required.…”

Section: Psoralen–ultraviolet a For Specific Dermatosesmentioning

confidence: 99%

Section: When Should Psoralen-ultraviolet a Be Used In Preference To mentioning

confidence: 99%

Section: When Should Psoralen-ultraviolet a Be Used In Preference To mentioning

confidence: 99%

Section: What Special Precautions Should Be Undertaken During Psoralementioning

confidence: 99%

See 3 more Smart Citations

British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of psoralen–ultraviolet A therapy 2015

et al. 2016

View full text Add to dashboard Cite

Chronic actinic dermatitis. An analysis of 51 patients evaluated in the United States and Japan

Lim

Morison

Kamide³

et al. 1994

Archives of Dermatology

View full text Add to dashboard Cite

Management of Chronic Photosensitive Eczema

Bilsland¹

1991

Arch Dermatol

View full text Add to dashboard Cite

To the Editor.\p=m-\Wehave read with interest a recent critique' of the human skin blanching assay. We are concerned about the accuracy of statements and the interpretation of results presented in this publication. Having successfully employed this bioassay for over 15 years, and having noted similar, productive usage of this optimized technique reported2,3 from laboratories worldwide, the negativism expressed in the critique could dissuade potential researchers from employing this extremely useful assay procedure.A major objection to our published methodology is that the intensity of blanching is estimated by the human eye. We agree that this is a highly subjective method, but we feel that if the optimized, double-blind methodology is rigidly applied, this problem is easily overcome. Emphasis has recently been made' of the alternative methods of reflectance spectrophotometry, laser Doppler velocimetry, and surface thermography as more accurate, objective techniques for the assessment of skin blanching. A later publication4 reports comparative data where direct correlation was found between reflectance spectrophotometry measurements and "subjective" visual observations. If this correlation is as good as the authors claim then there should, surely, be no further objection to the continued use of the visually assessed skin blanching response; the latter now having been proven several times to be as accurate as numerous instrumental methods. A good test of any experimental methodology is its durability. Visual blanching as¬ sessment has been in continual use for about 30 years. Other assessment methods seem to have been only of academic interest, appearing as comparative evaluations in the sci¬ entific literature, never to be practically utilized on an on¬ going basis, probably because present technology is cum¬ bersome, slow, expensive, and incapable of performing the number of observations per reading interval required by optimized methodology.2 Advocates of instrumental meth¬ ods are continually attempting to discredit the discrimina¬ tory ability of the eye, whereas their comparative evalua¬ tions have, without exception, shown the "subjective" visual observations to correlate directly with the "objective" instrumental measurements. We concede that it may be more expedient for new researchers to learn instrumental operation rather than gain experience in visual assessment through trial participation; however, once experienced, there is (currently) no match for the eye in terms of speed and convenience.Furthermore, in contrast to the comparative bioavailability results obtained from a single reading of blanching practiced in some laboratories, we have for many years advocated25 the use of a multiple-reading methodology and the subsequent generation of blanching response vs time profiles that are amenable to area under the curve analysis. Clinicians would certainly not accept a comparative drug bioavailability conclusion for other types of dosage form based on a single measurement after dosing; why, therefore, sho...

show abstract

Management of Chronic Photosensitive Eczema

Cited by 13 publications

References 8 publications

British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of psoralen–ultraviolet A therapy 2015

British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of psoralen–ultraviolet A therapy 2015

Chronic actinic dermatitis. An analysis of 51 patients evaluated in the United States and Japan

Management of Chronic Photosensitive Eczema

Contact Info

Product

Resources

About