Management of children and young people with headache

Whitehouse, William; Agrawal, Shakti

doi:10.1136/archdischild-2016-311803

Cited by 25 publications

(24 citation statements)

References 12 publications

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“…Our findings reinforce the conclusions expressed by authors of other recent literature reviews ( 6 , 7 ). We share the opinion that preventive drug treatment for headache is not always needed in young headache patients, and that the risk of side effects must always be taken into account.…”

Section: Discussionsupporting

confidence: 93%

“…In the rare instance when such effects have been reported for adults, they are noted to be short-lived and easily overcome ( 25 ). This stands in marked contrast to the array of side effects observed in drug prophylaxis, with the most common being sedation or somnolence, dizziness, mood/behavioral changes, constipation, increased appetite, and weight gain ( 6 , 23 ). Second, in recent years these treatments—particularly behavioral ones—have gained in popularity among adult patients, while conventional pharmacological treatments are being viewed as sometimes ineffective or too expensive ( 26 , 27 ).…”

Section: Discussionmentioning

confidence: 88%

“…As with adults, appropriate administration is needed in order to be effective, with specific attention being given to providing information about the risk for medication overuse headache ( 3 ). Among preventive drugs, antiepileptics such as topiramate, are considered as first-line treatment ( 4 ), and several drugs used in the prevention of migraine in adults are commonly prescribed for children ( 5 , 6 ). Side effects of particular relevance for children and adolescents include weight loss or weight gain, paresthesias, cognitive slowing, and sleepiness.…”

Section: Introductionmentioning

confidence: 99%

“…Caution is warranted in adolescent females in particular due to the elevated risk of developing polycystic ovarian syndrome as well as possible teratogenic effects of many of these compounds. Drug treatment, however, is not always needed, and prophylactic treatment is not considered the first line treatment in the vast majority of cases ( 6 , 7 ). In recent years, attention has been increasingly paid to non-pharmacological treatments of headache disorders, chiefly those that are cognitive, behavioral, or psychophysiological in nature, but with some attention to non-invasive neurostimulation ( 8 – 11 ).…”

Section: Introductionmentioning

confidence: 99%

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Non-pharmacological Approaches for Headaches in Young Age: An Updated Review

Andrasik

Grazzi²,

Sansone³

et al. 2018

Front. Neurol.

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Headache disorders are common in children and adolescents. Most of the studies on non-pharmacological treatments have however been carried out on adults. In this review we provide information on recent studies examining non-pharmacological approaches for managing headache in children and adolescents. Our search of SCOPUS for primary studies conducted between January 2010 and July 2018 uncovered 11 controlled studies, mostly addressing behavioral approaches, in which a total of 613 patients with a diagnosis of primary headache, and average age 10.2–15.7 years (30–89% females) were recruited. Non-pharmacological treatments were shown to produce sizeable effects on the classical primary endpoint, i.e., headache frequency, with reductions from baseline ranging between 34 and 78%. Among commonly reported secondary endpoints, particularly disability, quality of life, depression and anxiety, marked improvements were noted as well. Taken as a whole, our findings suggest that non-pharmacological treatments constitute a valid option for the prevention of primary headaches in young age. Future research with higher-quality studies is needed. Particular attention needs to be given to studies that randomize patients to condition, blind researchers in charge of evaluating treatment outcomes, routinely include headache frequency as the primary endpoint, include adequate-length follow-up, address changes in biomarkers of disease and other possible mediators of outcome, and that employ predictive models to enhance the level of evidence for these approaches.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Non-pharmacological Approaches for Headaches in Young Age: An Updated Review

Andrasik

Grazzi²,

Sansone³

et al. 2018

Front. Neurol.

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“…Клинические проявления инсульта у детей во многом аналогичны таковым у взрослых: мышечная слабость, нарушение чувствительности, речи, асимметрия лица; но диагностика инсульта на догоспитальном этапе значительно затруднена из-за часто неспецифической, «смазанной» клинической картины, которая может включать в себя разнообразные симптомы (головная боль, судороги, нарушение уровня сознания и другие), встречающиеся при широком спектре заболеваний не только центральной нервной системы, но и при болезнях других органов и систем (табл. 1) [17]. Дополнительные трудности в педиатрической популяции при диагностике инсульта связаны с поведенческими и возрастными особенностями.…”

Section: Introductionunclassified

Stroke in children and adolescents: topical problems of pre-hospital diagnostics

Хачатуров¹,

Щедеркина²,

Плавунов³

et al. 2020

Arhivʺ vnutrennej mediciny

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The article is devoted to the urgent problem of pediatrics and pediatric neurology, pre-hospital diagnosis of stroke in children. A review of domestic and foreign literature on the early diagnosis of stroke in children and adolescents, as well as epidemiological data on pediatric stroke, is presented. Particular attention is paid to the features of the symptoms of stroke and stroke-like conditions («stroke masks») in the pediatric population and the analysis of the main factors that influence errors in the early diagnosis of stroke in children and adolescents. Currently, in the diagnosis of ischemic stroke, its «masks» are found in 53.9 % of cases, with hemorrhagic stroke, in 36.3 %, and with transient ischemic attacks, in 9.8 % of cases. One of the most common diseases with which it is necessary to differentiate ischemic stroke in children is migraine. This problem is covered in academic writings that highlight the leading differential diagnostic criteria for migraine and stroke, and also represent a diagnostic algorithm. The clinical features of pediatric stroke, especially manifest symptoms, make it difficult to apply adult screening stroke scales in pediatrics. The article discusses the main scales for the early diagnosis of stroke in adults, and their potential application in pediatric practice. Currently accumulated experience in prehospital and early diagnosis of stroke in children determines the main directions of work to reduce the time of diagnosis of acute cerebrovascular accidents in children, followed by the introduction of reperfusion therapy in pediatric practice.

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