“…Three cases did not specify whether surgery was via a laparoscopic or open approach [ 18 , 27 , 29 ]. Complications (categorized according to the Clavien Dindo Classification; Supplementary Table 3 ) were reported in 29.5% (13/44) of surgical cases [ 6 , 8 , 18 , 22 , 41 , 43 , 44 , 46 , 47 , 50 , 59 , 61 ], including one post-operative fatality [ 61 ]. Three of the five most serious complications (Clavien Dindo Classification 4a, 4b, or 5) occurred in patients in whom surgery was performed as second-line treatment and endoscopic therapy had failed [ 6 , 22 , 41 ].…”