Management of atrial fibrillation

Gelzer, Anna R.; Kraus, Marc S.

doi:10.1016/j.cvsm.2004.05.001

Cited by 21 publications

(17 citation statements)

References 60 publications

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Section: The Most Common Complete Blood Count and Serum Biochemical Amentioning

confidence: 99%

“…A trial fibrillation is the most common atrial arrhythmia in domestic animal species. Atrial fibrillation is usually associated with underlying cardiac disease in dogs and cats 1 and with gastrointestinal disorders in cattle, but can be associated with no underlying cause, termed "lone" AF. 2 The incidence of arrhythmias in llamas has been reported to be 0.78-1.2%, as documented in 2 retrospective studies evaluating ECGs from 2,167 and 663 llamas, respectively.…”

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Atrial Fibrillation in Eight New World Camelids

Bozorgmanesh

Magdesian

Estell

et al. 2015

Veterinary Internal Medicne

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BackgroundThere is limited information on the incidence of clinical signs, concurrent illness and treatment options for atrial fibrillation (AF) in New World Camelids (NWC).ObjectiveDescribe clinical signs and outcome of AF in NWC.AnimalsEight New World Camelids admitted with AF.MethodsA retrospective observational study of camelids diagnosed with AF based on characteristic findings on electrocardiogram (ECG).ResultsAll animals had an irregularly irregular heart rhythm detected on physical examination and 4 cases had obtunded mentation on admission. Three camelids were diagnosed with AF secondary to oleander intoxication, 3 animals had underlying cardiovascular disease, 1 was diagnosed with lone AF and 1 had AF diagnosed on examination for a urethral obstruction. Five of eight animals survived to discharge and nonsurvivors consisted of animals which died or were euthanized as a result of cardiovascular disease (2/8) or extra‐cardiac disease unrelated to the AF (1/8).Conclusions and Clinical ImportanceAtrial fibrillation occurs in NWC in association with cardiovascular disease, extra‐cardiac disease or as lone AF. Amiodarone and transthoracic cardioversion were attempted in one llama with lone AF, but were unsuccessful. Atrial fibrillation was recorded in 0.1% of admissions.

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Section: The Most Common Complete Blood Count and Serum Biochemical Amentioning

confidence: 99%

mentioning

confidence: 99%

Atrial Fibrillation in Eight New World Camelids

Bozorgmanesh

Magdesian

Estell

et al. 2015

Veterinary Internal Medicne

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“…Atrial fibrillation (AF) is one of the most prevalent arrhythmia in dogs, affecting mainly large and giant breeds, and associates with high case fatality rates . Dogs with lone AF have a better survival than do those with concomitant heart disease, but the arrhythmia is strongly associated with dilated cardiomyopathy . Currently, several drugs and procedures exist to treat AF in dogs .…”

Section: Introductionmentioning

confidence: 99%

Efficacy of pentamidine analogue 6 in dogs with chronic atrial fibrillation

Szatmári

Yuan

Herwijnen

et al. 2018

Veterinary Internal Medicne

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BackgroundThe inward rectifier inhibitor pentamidine analogue 6 (PA‐6) is effective in cardioversion of goats with persistent rapid pacing induced atrial fibrillation (AF) and is not proarrhythmic in dogs with experimental chronic 3rd‐degree AV block. Efficacy and safety in the clinical setting are unknown.HypothesisThat PA‐6 would be effective in converting AF to sinus rhythm (SR) in dogs with naturally occurring AF, without the presence of overt adverse effects.AnimalsTen client‐owned large and giant breed dogs.MethodsAnimals with persistent or permanent AF were recruited for our prospective study. PA‐6 was administered IV as a bolus of 2.5 mg/kg 10 min−1 followed by a maintenance infusion of 0.04 mg/kg min−1 for a maximum of 50 minutes in conscious dogs. Standard 6 lead limb ECG was recorded during the infusion. Visible and audible signs of adverse effects were scored during the entire procedure.ResultsPA‐6 did not induce changes in QRS duration (54.7 ± 4.6 versus 56.7 ± 6.1 ms, P = .42), QTc interval (241.1 ± 19.5 versus 258.7 ± 19.8 ms, P = .061) or RR interval (363.4 ± 84.6 versus 440.8 ± 96.3 ms, P = .072) at the end of the bolus. No cardioversion to SR was observed in any dog. Three dogs displayed no adverse effects. Five dogs had premature ventricular depolarizations during PA‐6 infusion on the ECG. Respiratory distress with laryngeal stridor, subtle muscle twitching, and mild generalized muscular weakness were noncardiac adverse effects observed in 5 dogs. Adverse effects resolved spontaneously.Conclusions and Clinical importanceChronic naturally occurring AF in large and giant breed dogs could not be cardioverted to SR by PA‐6.

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“…AF is the most life threatening cardiac arrhythmia among canine and feline patients [3] , although presence of AF does not always accompany with a cardiac pathology. A poor prognosis in canine DCM can be related to AF [4] .…”

Section: Dear Editormentioning

confidence: 99%

“…According to literature [3,4] , symptomatic treatments such as intravenous lactated Ringer solution combined with 5% dextrose (10 ml/kg/hr) were given to rehydrate the patient, prednisolone (1 mg/ kg, q12h, PO), and amoxycillin clavulinate (20 mg/kg, q12h , PO) and digoxin (0.025 mg/kg, q24h, PO) was given in order to control AF in the patient.…”

Section: Dear Editormentioning

confidence: 99%