Management of atopic eczema in children aged up to 12 years: summary of NICE guidance

Lewis-Jones, Sue; Mugglestone, M. A.

doi:10.1136/bmj.39405.503773.ad

Cited by 64 publications

(40 citation statements)

References 5 publications

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“…The National Institute for Health and Clinical Excellence (NICE) guideline on the management of atopic eczema in children [32] proposed the adoption of a holistic approach to the assessment of a child’s atopic eczema, taking account of the physical severity of the eczema and its impact on QoL. This assessment should guide treatment decisions, and it was noted that no direct relation necessarily exists between physical severity of atopic eczema and impact on QoL.…”

Section: Hrqol Assessment In Dermatological Guidelinesmentioning

confidence: 99%

The Evolution of Quality of Life Assessment and Use in Dermatology

Chernyshov¹

2019

Dermatology

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The creation of the Dermatology Life Quality Index (DLQI) questionnaire facilitated many studies on the impact of skin diseases on patients’ quality of life (QoL). Many national and international guidelines recommend QoL assessment in dermatology, and some of them contain detailed recommendations on treatment goals and changes of treatment approaches based on DLQI score banding and minimal clinically important difference. The methodology of QoL in strument development and validation is constantly becoming more rigorous. Initiatives on selection of core outcome sets for skin diseases are focused on clinical trials but may also be beneficial for clinicians. There are various benefits of using QoL information in clinical practice, but experience of this is very limited at the moment. QoL assessment in dermatology is a rapidly developing field with a gradual shift from theory to practice.

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Section: Hrqol Assessment In Dermatological Guidelinesmentioning

confidence: 99%

The Evolution of Quality of Life Assessment and Use in Dermatology

Chernyshov¹

2019

Dermatology

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“…Whilst other nuclear receptor pathways for example NF-B have been shown to exert some control of inflammatory processes (Chen al., 2003), only calcineurin inhibitors have proved effective in suppressing organ rejection. Cyclosporine and FK-506 have since found success in a wide range of therapeutic contexts including rheumatoid arthritis, systemic lupus erythematosus, eczema and psoriasis so confirming the importance of calcineurin as an immunological drug target (Wells et al, 2000;Al-Daraji et al, 2002;Reynolds and Al-Daraji, 2002;Lewis-Jones and Mugglestone, 2007;Lampropoulos and D'Cruz, 2010).…”

Section: Introductionmentioning

confidence: 98%

Direct inhibition of calcineurin by caffeoyl phenylethanoid glycosides from Teucrium chamaedrys and Nepeta cataria

Prescott

Veitch

Simmonds

2011

Journal of Ethnopharmacology

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“…Aberrant T-cell activation is implicated in the pathogenesis of a variety of auto-immune conditions and there is strong clinical evidence to demonstrate the effectiveness of calcineurin inhibitors in controlling skin conditions such as eczema, psoriasis and systemic lupus erythematosus Reynolds and Al-Daraji, 2002;Lewis-Jones and Mugglestone, 2007;Lampropoulos and D'Cruz, 2010).…”

Section: Introductionmentioning

confidence: 99%