Management of anterior cruciate ligament tears in Tanner stage 1 and 2 children: a narrative review and treatment algorithm guided by ACL tear location

Turati, Marco; Rigamonti, L; Giulivi, Andrea; Gaddi, Diego; Accadbled, Franck; Zanchi, Nicolò; Brémond, Nicolas; Catalano, Marcello; Gorla, Massimo; Omeljaniuk, Robert J.; Zatti, Giovanni; Piatti, Massimiliano; Bigoni, Marco

doi:10.23736/s0022-4707.21.12783-5

Cited by 10 publications

(10 citation statements)

References 83 publications

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“…Interestingly, we observed that 10 miRNAs were detectable in both adult and adolescent groups with ACL tears without a meniscal tear. More pre-clinical studies are needed to better understand the intraarticular biochemical process in the healing potential of ACL tears in skeletally immature patients [ 41 , 42 , 43 , 44 , 45 ].…”

Section: Discussionmentioning

confidence: 99%

Characterization of microRNA Levels in Synovial Fluid from Knee Osteoarthritis and Anterior Cruciate Ligament Tears

et al. 2022

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This study investigated modifications of microRNA expression profiles in knee synovial fluid of patients with osteoarthritis (OA) and rupture of the anterior cruciate ligament (ACL). Twelve microRNAs (26a-5p, 27a-3p, let7a-5p, 140-5p, 146-5p, 155-5p, 16-5p,186-5p, 199a-3p, 210-3p, 205-5p, and 30b-5p) were measured by real-time quantitative polymerase chain reaction (RT-qPCR) in synovial fluids obtained from 30 patients with ACL tear and 18 patients with knee OA. These 12 miRNAs were chosen on the basis of their involvement in pathological processes of bone and cartilage. Our results show that miR-26a-5p, miR-186-5p, and miR-30b-5p were expressed in the majority of OA and ACL tear samples, whereas miR-199a-3p, miR-210-3p, and miR-205-5p were detectable only in a few samples. Interestingly, miR-140-5p was expressed in only one sample of thirty in the ACL tear group. miR-140-5p has been proposed to modulate two genes (BGN and COL5A1100) that are involved in ligamentous homeostasis; their altered expression could be linked with ACL rupture susceptibility. The expression of miR-30b-5p was higher in OA and chronic ACL groups compared to acute ACL samples. We provide evidence that specific miRNAs could be detected not only in synovial fluid of patients with OA, but also in post-traumatic ACL tears.

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Section: Discussionmentioning

confidence: 99%

Characterization of microRNA Levels in Synovial Fluid from Knee Osteoarthritis and Anterior Cruciate Ligament Tears

et al. 2022

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“…The lower the CRB, the higher the estimation accuracy that can be achieved. Therefore, it is hoped that, for the simulated indoor environment shown in Figure 2 , under the premise of meeting the indoor lighting conditions, by adjusting the different light source positions [ 8 ], the CRB of the surface to be measured is as small as possible, and then the position of the light source corresponding to the smallest CRB is found, that is [ 9 ], the light source layout with the best positioning performance [ 10 ].…”

Section: Introduction Of Characteristic Positioning Methodsmentioning

confidence: 99%

Research and Implementation of Indoor 3D Positioning Algorithm Based on LED Visible Light Communication and Corresponding Parameter Estimation

2022

Computational Intelligence and Neuroscience

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In the era of mobile Internet, the application of various positioning-based location service systems is becoming more and more common. In addition, the traditional radio positioning system is limited in the use of special environments such as mines, hospitals, and gas stations, and long-term electromagnetic radiation can cause potential damage to the human body. Compared with the traditional wireless positioning technology, VLC-based positioning technology has a good application prospect in the field of indoor wireless positioning. Compared with traditional radio positioning technology, the use of VLC technology to achieve indoor positioning is different in that the system design and layout need to consider the basic needs of indoor lighting; that is, the layout of multiple visible light sources in the room should meet the minimum illumination requirements of any area of the room. Since the layout structure of the light source that only considers the lighting requirements or only considers the positioning accuracy requirements is not the same, in the design process of the indoor visible light wireless positioning system, it is necessary to consider the overall optimization layout of multiple indoor visible light sources under the conditions of lighting and positioning constraints. This paper mainly optimizes indoor positioning from the aspects of light source layout, reflected light intensity distribution, and noise model.

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“…The characterization of the ACL tear level is important to take in consideration ACL repair surgery in case of proximal ACL tears. 59 In Type I and V is also important to distinguish two other categories: soft tissue ACL lesion or bony avulsion tear. Distal bony avulsion tears are further graded according to the Meyers-McKeever classification modified by Zaricznyj.…”

Section: Imagingmentioning

confidence: 99%

“…The characterization of the ACL tear level is important to take in consideration ACL repair surgery in case of proximal ACL tears. 59 …”

Section: Imagingmentioning

confidence: 99%

Pediatric anterior cruciate ligament tears and associated lesions: Epidemiology, diagnostic process, and imaging

Duart¹,

Rigamonti

Bigoni

et al. 2023

Journal of Children's Orthopaedics

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The incidence of anterior cruciate ligament injuries in skeletally immature patients has increased in recent years. The gold standard treatment of this type of trauma in children is not yet established. Conservative management may underestimate the risk of new meniscal and chondral tears; on the other hand, a more interventional approach may expose the patient to iatrogenic damage to the growth plate. A correct approach to the skeletally immature patient with knee trauma is therefore essential to guide the decision-making process. This review article aims to present an update on the epidemiology and diagnostic process of pediatric patients with anterior cruciate ligament tears and possible associated injuries. Level of Evidence: V.

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Management of anterior cruciate ligament tears in Tanner stage 1 and 2 children: a narrative review and treatment algorithm guided by ACL tear location

Cited by 10 publications

References 83 publications

Characterization of microRNA Levels in Synovial Fluid from Knee Osteoarthritis and Anterior Cruciate Ligament Tears

Characterization of microRNA Levels in Synovial Fluid from Knee Osteoarthritis and Anterior Cruciate Ligament Tears

Research and Implementation of Indoor 3D Positioning Algorithm Based on LED Visible Light Communication and Corresponding Parameter Estimation

Pediatric anterior cruciate ligament tears and associated lesions: Epidemiology, diagnostic process, and imaging

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