Management of a Solitary Bone Metastasis to the Tibia from Colorectal Cancer

Abstract

The onset of osseous metastases during the course of colorectal cancer is not common. When they appear they are usually combined with visceral metastases to the liver, lungs and brain. In our report we refer to the case of a 78-year-old patient who presented a solitary bone metastasis from rectal carcinoma in the middle of his right tibia. A year before he had been operated for a Dukes stage B1 adenocarcinoma of the rectum. The rest of the check was negative for other metastases. He received external radiotherapy and capecitabine with bisphosphonates as palliative treatment. 19 months after the original diagnosis of bone metastasis the patient has stable disease.

Bone metastasis

“…Chalkidou et al, reported a solitary tibial metastasis from rectal cancer 12 months after surgery. [7] In our case the metastasis was diagnosed 26 months after resection of the tumor. Survival after bone metastasis is very poor, with a median time of 5 months when associated with visceral metastasis also.…”

Day late and dollar short! Delayed recurrence of recto-sigmoid cancer involving sacrum and long term surveillance

“…Talbot et al [12] described a median time of 21 months and Chalkidou et al reported a solitary tibial metastasis from rectal cancer 12 months after surgery. [13] In our case the metastasis was diagnosed 13 years after resection of the tumour.…”

Solitary Osseous Metastasis of Rectal Carcinoma Masquerading as Osteogenic Sarcoma on Post-Chemotherapy Imaging: A Case Report

“…Skeletal metastases in patients with colorectal carcinoma are relatively uncommon with an incidence of 4.7-10.9% ( 2 ). A large retrospective study found an incidence of approximately 10% ( 4 ).…”

“…Colorectal cancer is one of the leading causes of cancer-related death worldwide ( 1 ). Skeletal metastases in patients with colon carcinoma are rare, and the occurrence of isolated an solitary skeletal metastasis in the absence of visceral metastases is even rarer ( 2 ). These metastases can have bizarre radiological appearances due to post-treatment changes.…”