Management and prevention of drug resistant infections in burn patients

Vinaik, Roohi; Barayan, Dalia; Shahrokhi, Shahriar; Jeschke, Marc G.

doi:10.1080/14787210.2019.1648208

Cited by 41 publications

(30 citation statements)

References 135 publications

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“…aureus MRSA infections in pus samples only; 11.2% of total pus-causing infections, while the Staph. aureus non-MDR formed 14.3%, the actual hazard of these infections are the résistance against antibiotics either community acquired infections or nosocomial infections in addition to the complications and cost of treatment and managing the infections [5,6,11,16,19].…”

Section: Discussionmentioning

confidence: 99%

“…The multidrug resistant bacteria in pus isolates formed 13.3% of all infections and the main causative agents were Acinetobacter spp (MDR) which resident in Jordan as a nosocomial infection cause of infection that explain the predominance of it in pus and chronic infections then S. aureus MRSA which is one of the main cause of wound over the world. (Table 4-C) [5,6,9,11,28].…”

Section: Pattern Of Pus Samplesmentioning

confidence: 99%

“…Despite their starting point, all injuries may transmitted by microorganisms or outside bodies or both to another area. Anaerobic microorganisms forms, 33% of the accumulated number of microbial species in colonized injuries, and their number increments increases to around half-in contaminated injuries [4][5][6][7]. Microbe of Pseudomonas aeruginosa could be one of the most causative agent for post-surgery wound infections, also the nosocomial infection which caused by multi-drug resistant, in the United [10].…”

Section: Introductionmentioning

confidence: 99%

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Multidrug Resistant Bacterial Profile and Patterns for Pus Isolates and Recurrent Wound Infections in Nongovernmental Hospitals of Jordan

Abu-Harirah

Amawi

Deeb

et al. 2021

JPRI

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Background: Many types of infection can cause pus Infections involving the bacteria; E.coli, so the assessment of multidrug Bacterial profile and patterns is needed to understand the source and management of these injuries. Purpose: To determine infections and patterns toward antibiotics of pus isolates and recurrent wound infections in nongovernmental hospitals of Jordan Methods: During period eleven months, 607 Patients were involved, out of which 128 patients had pus samples and/or recurrent wound infections. Data analysis was done using SPSS version 20. P value was set at <0.05. Results: One hundred twenty eight (21.1%) out of 607 patients were identified to had pus isolates and/or wound recurrent infections 86(87%) out of 128 patients had infections with known pathogenic microbes. Microbiological culture pattern was total of 19 different pathogenic microorganisms were isolated from the participants, with mixed gram-positive and gram-negative species; percentage of 37% gram-positive aerobic bacteria and 63% gram-negative aerobic bacteria. Conclusion: The global burden from multidrug resistant bacteria highly impacted in wound and pus-causing infections, either in hospital acquired infections or community acquired infections. The main causative agents of recurrent wound infection were Staph. aureus MRSA, E. coli, Pseudomonas aeruginosa, Acinetobacter spp (MDR). Gram-negative bacteria caused the most of infections by more than 67% comparing with gram-positive bacteria.

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Section: Discussionmentioning

confidence: 99%

Section: Pattern Of Pus Samplesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Multidrug Resistant Bacterial Profile and Patterns for Pus Isolates and Recurrent Wound Infections in Nongovernmental Hospitals of Jordan

Abu-Harirah

Amawi

Deeb

et al. 2021

JPRI

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“…In addition to Pseudomonas aeruginosa, MDR gram-negative bacteria and methicillin-resistant Staphylococcus aureus (MRSA) are the most common isolated infectious agents from complicated infected wounds [1][2][3] . Recent studies have shown that 20-50% of diabetic foot infections are due to MRSA 4,5 .…”

Section: Introductionmentioning

confidence: 99%

Multidrug-resistant Bacterial Profile and Patterns for Wound Infections in Nongovernmental Hospitals of Jordan

Abu-Harirah¹,

Qudah²,

Daabes³

et al. 2021

J. Pure Appl. Microbiol.

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Globally, multidrug-resistant bacteria affects wound infections, both hospital-acquired infections and community-acquired infections. The main isolates cultured from 607 subjects with wound infections were methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter spp. [multidrug resistant (MDR)]. Gram-negative bacteria caused most of the infections (67%) compared with gram-positive bacteria. Diabetic patients tend to have wound infections with mixed causative agents compared with non-diabetic patients.

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“…The topical treatment of a thermal burn wound mainly consists of reducing inflammation and bacterial colonization in the wound, reducing scarring and reparative tissue regeneration [ 1 , 2 , 3 ]. The wound healing depends on collagen formation [ 4 ], metabolism and immune status of the organism in general.…”

Section: Introductionmentioning

confidence: 99%

The New Pharmaceutical Compositions of Zinc Oxide Nanoparticles and Triterpenoids for the Burn Treatment

et al. 2020

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We studied oleogels containing zinc oxide nanoparticles (ZnO NPs) and lupane triterpenoids in sunflower oil for the treatment of burns. The modification of ZnO was carried out by treatment with alcohol solutions of betulin, betulonic acid, betulin diacetate and betulin diphosphate. The properties of modified ZnO NPs were studied by powder XRD (average sizes of 10–20 nm), FTIR (νZnO 450 cm−1), UV–vis (345–360 nm), and blue–violet emission (380–420 nm). The identification and assay of modified ZnO NPs and triterpenoids were estimated. The treatment by oleogels of deep II-degree burns was studied on rats using histological studies, Doppler flowmetry and evaluation of enzymes activity and malonic dialdehyde (MDA) level. After the action of oleogels, burn wound area, and the necrosis decreased twice on the 10th day in comparison with the 1st day after burn. The microcirculation index in the near-wound zone by 20–30% improved compared with the group without treatment. Evaluation of the enzyme activity and the MDA level after treatment by oleogels during the course of 10 days showed them returning to normal. The improvement of antioxidant biochemical indexes, as well as wounds’ healing, was mainly determined by the influence of zinc oxide nanoparticles.

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Management and prevention of drug resistant infections in burn patients

Cited by 41 publications

References 135 publications

Multidrug Resistant Bacterial Profile and Patterns for Pus Isolates and Recurrent Wound Infections in Nongovernmental Hospitals of Jordan

Multidrug Resistant Bacterial Profile and Patterns for Pus Isolates and Recurrent Wound Infections in Nongovernmental Hospitals of Jordan

Multidrug-resistant Bacterial Profile and Patterns for Wound Infections in Nongovernmental Hospitals of Jordan

The New Pharmaceutical Compositions of Zinc Oxide Nanoparticles and Triterpenoids for the Burn Treatment

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