Man-made vitreous fibers and workers' health. An overview of the epidemiologic evidence.

Saracci, Rodolfo; Simonato, Lorenzo

doi:10.5271/sjweh.2471

Cited by 11 publications

(4 citation statements)

References 4 publications

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“…Previous studies have shown an increased prevalence of respiratory symptoms, i.e. cough and phlegm among exposed workers, but not an increased risk for asthma [32,33]. The risk estimate in this study was rather high, even when controlling for interacting exposures.…”

Section: Welding Fumescontrasting

confidence: 71%

The risk of asthma in relation to occupational exposures: a case-control study from a Swedish city

Torén¹,

Balder²,

Brisman³

et al. 1999

Eur Respir J

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The purpose of this study was to estimate the risk of adult asthma in relation to certain occupational exposures.The study was designed as a case±control study in Go Èteborg, including 321 subjects with asthma, born between 1926 and 1970. Controls (n=1,459) were randomly selected from the same area from registers of the 1986 population. Questionnaire information was collected in 1996, and included occupational exposures and smoking habits. Odds ratios were calculated for exposure before asthma onset, stratified by sex and ageclass.The highest risks for asthma were associated with exposure to grain dust (odds ratio (OR) 4.2, 95% confidence interval (CI) 1.6±10.7) and flour dust (OR 2.8, 95% CI 1.1± 7.2). Among males, significantly increased risks were observed after exposure to flour dust, welding fumes, man-made mineral fibres, and solvents. Among females, increased risks for asthma were associated with exposures to paper dust and textile dust. In logistic regression models controlling for age, smoking, sex and interacting exposures, increased risks were seen for welding fumes (OR 2.0, 95% CI 15±3.4), manmade mineral fibres (OR 2.6, 95% CI 1.4±7.3) and solvents (OR 2.2, 95% CI 1.2±3.2). The fraction of asthma attributed to occupational exposures after adjusting for sex, smoking and age was 11% (95% CI 7±14%).In conclusion, exposure to welding fumes, man-made mineral fibres, solvents and textile dust is associated with increased risk for asthma. Eur Respir J 1999; 13: 496±501.

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Section: Welding Fumescontrasting

confidence: 71%

The risk of asthma in relation to occupational exposures: a case-control study from a Swedish city

Torén¹,

Balder²,

Brisman³

et al. 1999

Eur Respir J

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“…There were quite Dyspnoea >2*** 9 15 12 9 36 *P < 0-05; ***P < 0-001 between categories who smoked by the X2 test with 4 degrees of freedom. Eye irritation [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] (1-32 to 3-54) (1-7 to 4-08) < 0-0001 Skin irritation 1-25 (0-74 to 2-11) 3-18 (2-01 to 5-03) < 0-0001 large differences in smoking habits between plants even within the same country. The mean duration of employment was 10 2 years (range from plant to plant 7-2-13-8 years).…”

Section: Study Participantsmentioning

confidence: 99%

Study of the respiratory health of employees in seven European plants that manufacture ceramic fibres.

et al. 1995

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Objectives-To study the relation between occupational exposure to ceramic fibres during manufacture and respiratory health. Methods-The respiratory health of 628 current employees in the manufacture of ceramic fibres in seven European plants in three countries was studied with a respiratory questionnaire, lung function tests, and chest radiography. Simultaneous plant hygiene surveys measured subjects' current exposure to airborne ceramic fibres from personal samples with optical microscopy fibre counts. The measured exposures were combined with occupational histories to derive estimates of each subject's cumulative exposure to respirable fibres. Symptoms were related to current and cumulative exposure to ceramic fibres and lung function and findings from chest radiographs were related to cumulative exposure. Results-The mean duration of employment was 10-2 years and mean (range) cumulative exposure was 3-84 (0-22.94) (f.ml-'.y). Eye and skin symptoms were frequent in all plants and increased significantly, as did breathlessness and wheeze, with increasing current exposure. Dry cough and stuffy nose were less common in the least exposed group but did not increase with increasing exposure. After adjustment for the effects of age, sex, height, smoking, and past occupational exposures to respiratory hazards, there was a significant decrease in both forced expiratory volume in one second (FEV,) and forced midexpiratory flow related to cumulative exposure in current smokers (P < 0.05) and in FEV, in ex-smokers (P < 0.05). Small opacities were found in 13% of the chest radiographs; their prevalence was not related to cumulative exposure to ceramic fibres. Conclusions-It is concluded that exposure to ceramic fibres is associated with irritant symptoms similar to those seen in other exposures to man made mineral fibres (MMMFs) and that cumulative exposure to respirable ceramic fibres may cause airways obstruction by promoting the effects of cigarette smoke.

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“…These five studies include the two largest cohort studies already mentioned. In neither study and for none of the production types, was any relation of respiratory cancer to exposure duration and exposure intensity found (16).…”

Section: Resultsmentioning

confidence: 69%

Cancer incidence among employees in one mineral wool production plant in Denmark.

Ølsen¹,

Jensen²

1984

Scand J Work Environ Health

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Man-made vitreous fibers and workers' health. An overview of the epidemiologic evidence.

Abstract: SARACCI R, SIMONATO L. Man-made vitreous fibers and workers' health: An overview of the epidemiologic evidence. Scand j work environ health 8 (1982) 234-242.

Cited by 11 publications

References 4 publications

The risk of asthma in relation to occupational exposures: a case-control study from a Swedish city

The risk of asthma in relation to occupational exposures: a case-control study from a Swedish city

Study of the respiratory health of employees in seven European plants that manufacture ceramic fibres.

Cancer incidence among employees in one mineral wool production plant in Denmark.

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