Mammography, Magnetic Resonance Imaging of the Breast, and Radionuclide Imaging of the Breast

Whitman, Gary J.; Kushwaha, Anne C.

doi:10.1007/978-0-387-34952-7_4

Cited by 1 publication

(3 citation statements)

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“…Most women who will be diagnosed with ductal carcinoma in situ have tumors detected through mammography [4], suggesting a prominent role for screening in the detection of this malignancy. The goal of the mammogram is to detect small masses <1 cm and calcifications [5]. Although lobular carcinoma in situ is not detectable by mammography [6], it can be assessed through core needle or excision biopsy.…”

Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

“…Lobular carcinoma in situ is unique because these tumors are not typically discovered as palpable masses and can present as mammographic calcification [7], which is why routine mammography is so important. The detection of calcification requires further analysis through additional diagnostic imaging, magnification views, sonography, 6-month followup exams, or biopsy [5]. …”

Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

“…Further independent recommendations for the high risk group are for an additional annual screening using MRI, which is more sensitive at detecting carcinomas than both sonography and mammography, particularly in those with dense breasts. The drawbacks to MRI include the reduced detection of calcifications, the higher cost associated, and the increased time required by the instrumentation [5]. …”

Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

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The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers: Current Trends in Technology and Future Opportunities

Breuer

Murph

2011

International Journal of Proteomics

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Technological and scientific innovations over the last decade have greatly contributed to improved diagnostics, predictive models, and prognosis among cancers affecting women. In fact, an explosion of information in these areas has almost assured future generations that outcomes in cancer will continue to improve. Herein we discuss the current status of breast, cervical, and ovarian cancers as it relates to screening, disease diagnosis, and treatment options. Among the differences in these cancers, it is striking that breast cancer has multiple predictive tests based upon tumor biomarkers and sophisticated, individualized options for prescription therapeutics while ovarian cancer lacks these tools. In addition, cervical cancer leads the way in innovative, cancer-preventative vaccines and multiple screening options to prevent disease progression. For each of these malignancies, emerging proteomic technologies based upon mass spectrometry, stable isotope labeling with amino acids, high-throughput ELISA, tissue or protein microarray techniques, and click chemistry in the pursuit of activity-based profiling can pioneer the next generation of discovery. We will discuss six of the latest techniques to understand proteomics in cancer and highlight research utilizing these techniques with the goal of improvement in the management of women’s cancers.

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Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

Section: Breast Cancer Screening and Detectionmentioning

confidence: 99%

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