Mammography at reduced doses: present performance and future possibilities

Ep, Muntz; Wilkinson, Evelyn E.; Fw, George

doi:10.2214/ajr.134.4.741

Cited by 13 publications

(3 citation statements)

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“…Comparison of our estimated values of glandular tissue dose from mammography over time with those described by other investigators for the same time-periods for women with 5 cm CBT demonstrates consistencies for periods following 1970 (12,85,86,87 quoting 58) but several reported glandular tissue dose estimates for periods before 1970 (12,86,87 quoting 58) were higher than our estimates of the average value of mean glandular dose (but were included within our upper bound). It is difficult to determine reasons for this difference, particularly because most publications of earlier doses lacked detailed documentation of the basis of their estimates (12,86) and did not quantitatively derive dose estimates over the range of CBT as done in our analysis.…”

Section: Discussionsupporting

confidence: 71%

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Reconstruction of Absorbed Doses to Fibroglandular Tissue of the Breast of Women Undergoing Mammography (1960 to the Present)

Thierry-Chef

Simon

Weinstock³

et al. 2012

Radiation Research

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The assessment of potential benefits versus harms from mammographic examinations as described in the controversial breast cancer screening recommendations of the U.S. Preventive Task Force included limited consideration of absorbed dose to the fibroglandular tissue of the breast (glandular tissue dose), the tissue at risk for breast cancer. Epidemiological studies on cancer risks associated with diagnostic radiological examinations often lack accurate information on glandular tissue dose, and there is a clear need for better estimates of these doses. Our objective was to develop a quantitative summary of glandular tissue doses from mammography by considering sources of variation over time in key parameters including imaging protocols, x-ray target materials, voltage, filtration, incident air kerma, compressed breast thickness, and breast composition. We estimated the minimum, maximum, and mean values for glandular tissue dose for populations of exposed women within 5-year periods from 1960 to the present, with the minimum to maximum range likely including 90% to 95% of the entirety of the dose range from mammography in North America and Europe. Glandular tissue dose from a single view in mammography is presently about 2 mGy, about one-sixth the dose in the 1960s. The ratio of our estimates of maximum to minimum glandular tissue doses for average-size breasts was about 100 in the 1960s compared to a ratio of about 5 in recent years. Findings from our analysis provide quantitative information on glandular tissue doses from mammographic examinations which can be used in epidemiologic studies of breast cancer.

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Section: Discussionsupporting

confidence: 71%

“…It is difficult to determine reasons for this difference, particularly because most publications of earlier doses lacked detailed documentation of the basis of their estimates (12,86) and did not quantitatively derive dose estimates over the range of CBT as done in our analysis.…”

Section: Discussionmentioning

confidence: 97%

Reconstruction of Absorbed Doses to Fibroglandular Tissue of the Breast of Women Undergoing Mammography (1960 to the Present)

Thierry-Chef

Simon

Weinstock³

et al. 2012

Radiation Research

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“…A calculated primary spectrum for the reference system as well as reference conditions are discussed in [23]. Following [24], a reference system employing a microfocus tube with a tungsten target, 0.25 mm Al inherent filtration, and 0.25 mm Al added filtration was selected. The maximum tube potential was assumed to be 25 kVp with a focal spot aperture of 0.0177 mm2.…”

Section: Reference Systemmentioning

confidence: 99%

The Sensitivity to Technological Innovations of the Doses Delivered by Optimized Mammography Systems

Jafroudi¹,

Muntz²

1986

IEEE Trans. Med. Imaging

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Multiparameter optimizations have been carried out to study the effects of hypothetical technological advances on the patient doses required to maintain a given image quality in mammography. The assumed advances include: improvement in the power loading limits of the tube focal spot, increased absorption efficiency for a given detector resolution, increases in detector system gain, and changes in the exposure time limitations that result from patient motion. The optimization permits system geometry, kVp of the examination, filtration, detector resolution, focal spot size, and grid characteristics to vary simultaneously and self-consistently subject to image quality as well as technological constraints. The effects of technological innovations were measured by systematically varying the technological constraints to reflect hypothetical improvements and comparing the resulting minimized doses, required to maintain constant image quality, to a baseline optimized system derived from a set of baseline technological capabilities.

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Mammography: Overview

Friedrich¹

1981

Radiology Today

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Mammography at reduced doses: present performance and future possibilities

Cited by 13 publications

References 0 publications

Reconstruction of Absorbed Doses to Fibroglandular Tissue of the Breast of Women Undergoing Mammography (1960 to the Present)

Reconstruction of Absorbed Doses to Fibroglandular Tissue of the Breast of Women Undergoing Mammography (1960 to the Present)

The Sensitivity to Technological Innovations of the Doses Delivered by Optimized Mammography Systems

Mammography: Overview

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