Mammary mucinous cystadenocarcinoma

Coyne, John; Irion, Luciane

doi:10.1111/j.1365-2559.2006.02471.x

Cited by 24 publications

(34 citation statements)

References 6 publications

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“…Except one ER positive tumor, all reported cases of MCA were hormone status negative [1,2,4,[7][8][9][10][11][12][13]. Based on this immunohistochemical finding, primary MCAs of the breast were thought to occur regardless of the estrogenic stimulation [2,4,10].…”

Section: Discussionmentioning

confidence: 99%

“…Although majority of the reported cases were hormone receptors negative and had high Ki-67 proliferation index [1,2,7,8,[10][11][12] which indicate poor prognosis, no recurrences and no disease-related death were detected in the follow-ups [2]. Lymph node metastases was only found in three cases [1,2,12].…”

Section: Discussionmentioning

confidence: 99%

“…Although the cases of MCA which were reported to be ER, PR and CerbB2 negative and which had a high Ki-67 index were not followed-up long-term, they showed good prognosis [2,3,7]. MCA of the breast with different pathogenesis and biological behavior should be differentiated from other histological subtypes of the primary breast cancers and from the metastases of the other organ tumors.…”

Section: Discussionmentioning

confidence: 99%

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Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH – and review of the literature

Kucukzeybek¹,

Yiğit²,

Sarı³

et al. 2014

pjp

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Fifty five-years-old woman was presented to the general surgery upon the palpation of a mass in her left breast. In the excisional biopsy performed, partially cystic tumor of 2 × 1 cm with solid areas was macroscopically observed. After through microscopic examination, the patient was diagnosed as invasive mucinous cystadenocarcinoma and the tumor was found to be ER-and PR-negative and C-erbB2 (2+). In the fluorescent in situ hybridization, HER2/neu gene amplification was observed. Here, we present the clinical, cytological, morphological and immunohistochemical features of a very rare type of breast carcinoma, mucinous cystadenocarcinoma of the breast, with the review of the relevant literature.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH – and review of the literature

Kucukzeybek¹,

Yiğit²,

Sarı³

et al. 2014

pjp

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“…1,3 Be ca u se MCA is an ex tre mely ra re va ri ant of bre ast car ci no ma, so me ca ses may ha ve be en miscla si fi ed as ot her bre ast car ci no mas. We want to pre sent a ca se who was hor mon de pen dent in con trast to pre vi o usly re por ted ca ses.…”

Section: Discussionmentioning

confidence: 99%

“…All of them were hormon independent tumors. 3 We wish to document an additional and hormon dependent case. The informed consent of the patient was obtained for this case report.…”

mentioning

confidence: 99%

Mucinous Cystadenocarcinoma: A Rare Variant of Breast Carcinoma: Case Report

Pak¹,

Camlibel²,

Atalay³

et al. 2010

Turkiye Klinikleri J Med Sci

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Pure mucinous adenocarcinoma of the breast with the rare lymphoplasmacytic infiltration: A case report with review of literature

Prajapati,

Bhabhor,

Mehta

et al. 2024

Clinical Case Reports

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Key Clinical MessageA unique ER/PR‐positive mucinous adenocarcinoma of breast but CK7/CK20 negativity. A rare finding of Lymphoplasmacytic Infiltration is noted. Successful treatment included modified radical mastectomy and tamoxifen‐based therapy, leads to remission.AbstractMucinous carcinoma, which is characterized by the presence of abundant extracellular mucin, is a rare and distinctive subtype of invasive breast cancer. This subtype accounts for less than 5% of all invasive breast cancers, with pure mucinous carcinoma representing only around 2%. It is most commonly found in older patients, typically in the sixth to early eighth decade of life. We present the case of a 55‐year‐old female with a 15‐year history of a painless, gradually enlarging palpable lump on her left breast. Upon examination, a 5 × 5 cm lump with well‐defined margins and a hard consistency was found in the lower outer quadrant of the left breast. Histopathological examination confirmed a diagnosis of Mucinous Adenocarcinoma of the Left Breast. The patient underwent modified radical mastectomy and received adjuvant endocrine therapy with tamoxifen due to hormone receptor‐positive status. Mucinous carcinoma of the breast is a unique entity with specific histological features including the presence of extracellular mucin pools. Immunohistochemical staining is crucial for determining hormone receptor status, which can guide treatment decisions. Although surgical intervention is the primary approach, the extent of surgery may vary, ranging from lumpectomy to mastectomy. Adjuvant therapies such as chemotherapy and radiotherapy may also be considered based on individual cases. This case underscores the importance of a multidisciplinary approach in managing rare subtypes of breast cancer, such as mucinous carcinoma. Accurate diagnosis, appropriate surgical intervention, adjuvant therapy, and long‐term follow‐up are critical components of treatment.

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Mammary mucinous cystadenocarcinoma

Cited by 24 publications

References 6 publications

Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH – and review of the literature

Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH – and review of the literature

Mucinous Cystadenocarcinoma: A Rare Variant of Breast Carcinoma: Case Report

Pure mucinous adenocarcinoma of the breast with the rare lymphoplasmacytic infiltration: A case report with review of literature

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