Mammary duct ectasia in children: Report of a short series and review of the literature

McHoney, Merrill; Munro, Fraser D.; MacKinlay, Gordon A.

doi:10.1016/j.earlhumdev.2011.04.005

Cited by 33 publications

(28 citation statements)

References 15 publications

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“…2 Es más frecuente en los varones, con una relación 10:4. 4 Hasta el momento no se conoce la causa y se han propuesto estímulos hormonales, anomalías estructurales del tejido mamario, infecciones y, en un trabajo publicado recientemente, hematopoyesis extramedular. 3 Para algunos autores el paso de hormonas por vía transplacentaria o a través de la leche materna podría estar implicado en el desarrollo de la ectasia.…”

Section: Discussionunclassified

“…De esta forma los estrógenos generarían el crecimiento del sistema ductal y la progesterona el de los alvéolos mamarios. [1][2][3][4][5][6][7] Esta hipótesis no ha sido demostrada y se han publicado casos tanto en lactantes alimentados con pecho como con fórmulas artificiales. En ninguno de los pacientes descritos habían aumentado los valores de estas hormonas.…”

Section: Discussionunclassified

“…[1][2][3][4][5] Presentamos dos casos clínicos de lactantes con sangrado por el pezón con evolución típica de ectasia ductal benigna.…”

Section: Introductionunclassified

See 2 more Smart Citations

Telorragia en el lactante por ectasia ductal. Consideraciones acerca de dos casos

Affranchino¹,

Oglietti²,

Amoedo³

et al. 2013

Arch Argent Pediat

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RESUMENLa descarga de sangre a través del pezón (telorragia) es un síntoma muy infrecuente en pediatría. Si bien genera gran preocupación y alarma por su equivocada asociación con el carcinoma de pacientes adultos, en los niños se asocia, en la mayoría de los casos, con una ectasia ductal benigna. Hasta el momento, sólo existen informes o series de casos y, aunque se proponen diferentes teorías, la causa no se conoce con exactitud. Se presentan dos casos con características clínicas y evolución muy similar, en los que el sangrado se resolvió en forma espontánea, uno en cuatro y el otro en seis semanas. Se realiza una revisión del tema y, dado que se trata de un proceso benigno y autolimitado, se sugiere, en ausencia de otros hallazgos en el examen físico, realizar estudios mínimamente invasivos, adoptar una conducta expectante y tranquilizar a la familia en la espera de una resolución espontánea. Palabras clave: telorragia, ectasia ductal, sangrado a través del pezón. SUMMARYBloody discharge from the nipple (thelorrhagia) is a rare symptom in childhood and is a cause of great concern due to the mistaken association with carcinoma in adults. However, in children thelorrhagia is due to benign mammary duct ectasia in the majority of cases. Up to date, only isolated case reports or case series have been published and, although different theories have been postulated, no definite etiology has been identified. We report two cases with similar clinical features and outcome, in whom bleeding resolved spontaneously 4 and 6 weeks after onset. We present a review of the literature. Based on the benign and self-limiting process and in the absence of other findings on physical examination, we suggest a watch-and-wait approach with minimally invasive studies and reassurance and support for the family as most cases resolve spontaneously.

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Section: Discussionunclassified

See 1 more Smart Citation

Telorragia en el lactante por ectasia ductal. Consideraciones acerca de dos casos

Affranchino¹,

Oglietti²,

Amoedo³

et al. 2013

Arch Argent Pediat

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“…The ducts contain eosinophilic granular secretions and foamy histiocytes (1) . Ductectasia affects primarily middle-aged to elderly women but can occasionally occur in children (2) . Nipple discharge is the third most common reason for presentation to a breast clinic (3) .…”

Section: Introductionmentioning

confidence: 99%

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

2017

IJMS

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“…MDE typically occurs in females undergoing menopause, but can also occur in younger females, males and infants. The disease usually affects mammary ducts that are large or medium in size, and is one of the most prevalent causes of bloody nipple discharge and sub-areolar masses, radiologically and clinically mimicking invasive carcinoma (1,4,5). The treatment of MDE is usually conservative.…”

Section: Introductionmentioning

confidence: 99%

Bilateral mammary duct ectasia induced by sulpiride-associated hyperprolactinemia: A case report

et al. 2015

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Abstract.A 32 year old female diagnosed with schizophrenia was treated with sulpiride, trihexyphenidyl and alprazolam for 6 years. A physical examination revealed bilateral nipple retraction and a non-tender mass in the left breast, with little nipple discharge. Tests revealed high levels of carbohydrate antigen 125, serum prolactin and testosterone levels, and ultrasound revealed a number of masses in the bilateral breasts; the largest mass (2.2x1.3 cm) was located in the left breast. A rich blood flow signal was identified around the nodule. The ducts in the bilateral breasts exhibited cystic ectasia. Multiple enlarged lymph nodes were found in the bilateral axillae. Mammography revealed thickened breast tissue without an evident mass, and calcification. A segmental mastectomy was performed and subsequent histological examination revealed multiple dilated ducts, the largest of which contained eosinophilic material. The pathological diagnosis was of breast duct dilatation. Bacterial culture and drug sensitivity analysis of the secretions from the cystic cavity revealed no bacterial growth, and an acid fast bacillus stain was negative. Extravasation of the surgical wound occurred 1 month later, and Staphylococcus epidermidis was observed using a bacterial culture. This was treated with moxifloxacin for 1 week. It was suggested that the patient should switch to a prolactin sparing antipsychotic in view of the hyperprolactinemia, however, the patient refused. After a clinical follow-up of 16 months, the wound had healed well and no palpable mass was found in the breast.

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Mammary duct ectasia in children: Report of a short series and review of the literature

Cited by 33 publications

References 15 publications

Telorragia en el lactante por ectasia ductal. Consideraciones acerca de dos casos

Telorragia en el lactante por ectasia ductal. Consideraciones acerca de dos casos

Ductectasia of the Breast; An Experience With Hadfield Operation (Radical Excision of the Subareolar Duct System)

Bilateral mammary duct ectasia induced by sulpiride-associated hyperprolactinemia: A case report

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