Malnutrition-Inflammation Score VS Phase Angle in the Era of GLIM Criteria: A Cross-Sectional Study among Hemodialysis Patients in UAE

Abstract

(1) Background: Malnutrition is prevalent in hemodialysis (HD) patients and is associated with an increased risk of morbidity and mortality. The aim of this study was to explore the prevalence of malnutrition using the malnutrition-inflammation score (MIS) and phase angle (PhA) and compare their concordance with the new Global Leadership Initiative on Malnutrition (GLIM) criteria for the diagnosis of malnutrition. (2) Methods: Seventy HD patients were assessed. Malnutrition was diagnosed based on the GLIM criteria and MIS questionnaire. The agreement between the diagnostic tools (MIS, PhA derived from the bioelectrical impedance analysis (BIA), and GLIM criteria) was assessed. The optimal gender-specific cutoff points were identified for the PhA according to the GLIM criteria. (3) Results: Almost half of the sample was diagnosed as malnourished according to the MIS (48.57%) and GLIM criteria (54.29%). A fair agreement was observed between the GLIM criteria, MIS (k = 0.202), and PhA (k = 0.279) among the malnourished patients. The PhA had better sensitivity but worse specificity compared to the MIS. The optimum cutoff points of PhA to detect malnutrition according to the GLIM criteria were a PhA value of ≤5.7° for males and ≤3.8° for females. (4) Conclusion: The MIS performed slightly better than PhA in the diagnosis of malnutrition among HD patients within the spectrum of the GLIM criteria.

A Comparative Analysis of Nutritional Assessment Using Global Leadership Initiative on Malnutrition Versus Subjective Global Assessment and Malnutrition Inflammation Score in Maintenance Hemodialysis Patients

“…This variability resulted only in a fair agreement between 7p-SGA and MIS with GLIM, with poor diagnostic accuracy for GLIM, characterized by AUC ranging from 0.61 to 0.68. This finding is similar to that found by Karavetian et al 15 in which there was a fair agreement between GLIM and MIS (kappa 5 0.202) and a higher prevalence of malnutrition by GLIM (54.3%) than by MIS (48.6%) in adult MHD patients. The difference in structure between the tools likely played an important role in these findings.…”

Predicational ability of phase angle on protein energy wasting in kidney disease patients with renal replacement therapy: A cross‐sectional study

“…Karavetian et al. (2019) according to the ROC cutoff points, Chi‐square test was conducted between PEW and non‐PEW groups. OR and 95% CI were calculated in prediction of PEW.…”

“…Considering M-BIA as predictor in the evaluation of health in populations (Norman et al, 2012;Powrózek et al, 2019;, our result also indicated that PA can be used as independent factor associated with malnutrition in CKD patients. Karavetian et al (2019)…”

Evaluation of the Global Leadership Initiative on Malnutrition Criteria Using Different Muscle Mass Indices for Diagnosing Malnutrition and Predicting Survival in Lung Cancer Patients

“…Recently, the Global Leadership Initiative on Malnutrition (GLIM), a set of guidelines for diagnosing malnutrition, was proposed 18 . Previous studies proved the effectiveness of these guidelines in identifying malnutrition 20‐22 . However, validation of the value of the GLIM guidelines in cancer patients remains scare 23 .…”

“…18 Previous studies proved the effectiveness of these guidelines in identifying malnutrition. [20][21][22] However, validation of the value of the GLIM guidelines in cancer patients remains scare. 23 And there has not been a study that has evaluated its role in determining the prognosis of LC patients.…”